CYT387 restores Th17/Treg cell balance and inhibits mature osteoclast cell formation by regulating SOX-5 signaling in rheumatoid arthritis

CYT387 restores Th17/Treg cell balance and inhibits mature osteoclast cell formation by regulating SOX-5 signaling in rheumatoid arthritis

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The present study was conducted to investigate the therapeutic efficacy of CYT387 in rheumatoid arthritis pathogenesis concerning T helper 17 cell/regulatory T cell (Th17/Treg) imbalance and osteoclastogenesis. In this study, CYT 387 inhibited the proliferation of Th17 cells and collectively reloca...

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Bibliographic Details
Main Authors:	Susmita Srivastava, Mahaboobkhan Rasool
Format:	Article
Language:	English
Published:	Bangladesh Pharmacological Society 2023-12-01
Series:	Bangladesh Journal of Pharmacology
Subjects:	T helper 17 (Th17) cell osteoclastogenesis CYT387 IL-6 trans-signaling janus kinases rheumatoid arthritis
Online Access:	https://asiajol.info/index.php/BJP/article/view/68901

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