Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism
Abstract Peroxisomes play a central role in tuning metabolic and signaling programs in a tissue- and cell-type-specific manner. However, the mechanisms by which the status of peroxisomes is communicated and integrated into cellular signaling pathways are not yet understood. Herein, we report the cel...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-09-01
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Series: | Biology Direct |
Online Access: | https://doi.org/10.1186/s13062-023-00416-3 |