Oxidized cholesterol as the driving force behind the development of Alzheimer’s disease

Oxidized cholesterol as the driving force behind the development of Alzheimer’s disease

Alzheimer’s disease (AD), the most common neurodegenerative disorder associated with dementia, is typified by the pathological accumulation of amyloid β peptides and neurofibrillary tangles within the brain. Considerable evidence indicates that many events contribute to AD progression, including oxi...

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Bibliographic Details
Main Authors: Paola eGamba, Gabriella eTesta, Simona eGargiulo, Erica eStaurenghi, Giuseppe ePoli, Gabriella eLeonarduzzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Cholesterol
Inflammation
Oxidative Stress
Alzheimer’s disease
oxysterols
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00119/full

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