Visceral leishmaniasis in the Metropolitan Region of Belo Horizonte, State of Minas Gerais, Brazil

In the last few years the number of human cases of American visceral leishmaniasis in the Metropolitan Region of Belo Horizonte (MRBH), Minas Gerais, Brazil has increased, indicating an elevation in the transmission rate of the disease. The total number of notified human cases in the MRBH since 1994...

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Main Authors: Eduardo S Silva, Célia MF Gontijo, Raquel S Pacheco, Vanessa OP Fiuza, Reginaldo P Brazil
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2001-04-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000300002
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author Eduardo S Silva
Célia MF Gontijo
Raquel S Pacheco
Vanessa OP Fiuza
Reginaldo P Brazil
author_facet Eduardo S Silva
Célia MF Gontijo
Raquel S Pacheco
Vanessa OP Fiuza
Reginaldo P Brazil
author_sort Eduardo S Silva
collection DOAJ
description In the last few years the number of human cases of American visceral leishmaniasis in the Metropolitan Region of Belo Horizonte (MRBH), Minas Gerais, Brazil has increased, indicating an elevation in the transmission rate of the disease. The total number of notified human cases in the MRBH since 1994, when the first case was identified, up to 1999 was 345 of which 223 (65%) were from the city itself, indicating an urbanization of the disease in this region of Minas Gerais. The age distribution of visceral leishmaniasis cases in the MRBH shows a higher prevalence in children from 0-4 years old, responsible for 28.9% of the notifications. Clinical and immunological findings from dogs infected with Leishmania chagasi are described. The majority of these animals showed no sign of the disease. Sera from all infected dogs showed detectable Leishmania-induced high titles of antibodies based on the results of an indirect fluorescent antibody test. Samples of isolated Leishmania from human and dogs were characterized as L. (L.) chagasi by biochemical and molecular techniques.
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spelling doaj.art-be39bd52af88448cab57ebab77b004042023-09-02T13:54:06ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602001-04-0196328529110.1590/S0074-02762001000300002Visceral leishmaniasis in the Metropolitan Region of Belo Horizonte, State of Minas Gerais, BrazilEduardo S SilvaCélia MF GontijoRaquel S PachecoVanessa OP FiuzaReginaldo P BrazilIn the last few years the number of human cases of American visceral leishmaniasis in the Metropolitan Region of Belo Horizonte (MRBH), Minas Gerais, Brazil has increased, indicating an elevation in the transmission rate of the disease. The total number of notified human cases in the MRBH since 1994, when the first case was identified, up to 1999 was 345 of which 223 (65%) were from the city itself, indicating an urbanization of the disease in this region of Minas Gerais. The age distribution of visceral leishmaniasis cases in the MRBH shows a higher prevalence in children from 0-4 years old, responsible for 28.9% of the notifications. Clinical and immunological findings from dogs infected with Leishmania chagasi are described. The majority of these animals showed no sign of the disease. Sera from all infected dogs showed detectable Leishmania-induced high titles of antibodies based on the results of an indirect fluorescent antibody test. Samples of isolated Leishmania from human and dogs were characterized as L. (L.) chagasi by biochemical and molecular techniques.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000300002visceral leishmaniasisepidemiologyhuman - dogsLeishmania chagasiMinas GeraisBrazil
spellingShingle Eduardo S Silva
Célia MF Gontijo
Raquel S Pacheco
Vanessa OP Fiuza
Reginaldo P Brazil
Visceral leishmaniasis in the Metropolitan Region of Belo Horizonte, State of Minas Gerais, Brazil
Memorias do Instituto Oswaldo Cruz
visceral leishmaniasis
epidemiology
human - dogs
Leishmania chagasi
Minas Gerais
Brazil
title Visceral leishmaniasis in the Metropolitan Region of Belo Horizonte, State of Minas Gerais, Brazil
title_full Visceral leishmaniasis in the Metropolitan Region of Belo Horizonte, State of Minas Gerais, Brazil
title_fullStr Visceral leishmaniasis in the Metropolitan Region of Belo Horizonte, State of Minas Gerais, Brazil
title_full_unstemmed Visceral leishmaniasis in the Metropolitan Region of Belo Horizonte, State of Minas Gerais, Brazil
title_short Visceral leishmaniasis in the Metropolitan Region of Belo Horizonte, State of Minas Gerais, Brazil
title_sort visceral leishmaniasis in the metropolitan region of belo horizonte state of minas gerais brazil
topic visceral leishmaniasis
epidemiology
human - dogs
Leishmania chagasi
Minas Gerais
Brazil
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000300002
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