Correlation between microbial characteristics and reproductive status of the yak uterus based on macrogenomic analysis
Abstract Introduction This study aimed to investigate the microbial characteristics of yak uteri collected using intrauterine cotton swabs (CS) during different reproductive stages and the correlation of these microbial characteristics with reproductive status. Methods We used a macrogenomic approac...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-01-01
|
| Series: | BMC Veterinary Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12917-023-03845-4 |
| _version_ | 1797363191847583744 |
|---|---|
| author | Rui Wang Meng Wang Qiaoying Zeng Libin Wang Qian Zhang Sisi Pu Xin Ma Jinglei Wang Yangyang Pan |
| author_facet | Rui Wang Meng Wang Qiaoying Zeng Libin Wang Qian Zhang Sisi Pu Xin Ma Jinglei Wang Yangyang Pan |
| author_sort | Rui Wang |
| collection | DOAJ |
| description | Abstract Introduction This study aimed to investigate the microbial characteristics of yak uteri collected using intrauterine cotton swabs (CS) during different reproductive stages and the correlation of these microbial characteristics with reproductive status. Methods We used a macrogenomic approach to analyze the functional aspects of different microorganisms in samples collected during the pre-estrus, estrus, late estrus, and diestrus stages. Results The results revealed the presence of 1293 microbial genera and 3401 microbial species in the uteri of yaks at different reproductive stages. The dominant bacterial species varied across the different periods, with Micrococcus and Proteus being dominant during pre-estrus; Pseudomonas, Clostridium, Flavobacterium, Bacillus, and Staphylococcus during estrus; Acinetobacter, Bacillus and Proteus during late estrus; and Pseudomonas, Escherichia coli, and Proteus during diestrus. Discussion The primary functions of these bacteria are enriched in various metabolic pathways, including carbohydrate and amino acid metabolism, intracellular transport and secretion, post-translational protein modification, and drug resistance. These findings suggest that the microbial diversity in the uterus of yaks plays a crucial role in reproductive regulation and can help prevent reproductive tract-related diseases. |
| first_indexed | 2024-03-08T16:17:38Z |
| format | Article |
| id | doaj.art-be3ce4bf93f0424b92a981625576f922 |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-03-08T16:17:38Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj.art-be3ce4bf93f0424b92a981625576f9222024-01-07T12:30:31ZengBMCBMC Veterinary Research1746-61482024-01-0120111410.1186/s12917-023-03845-4Correlation between microbial characteristics and reproductive status of the yak uterus based on macrogenomic analysisRui Wang0Meng Wang1Qiaoying Zeng2Libin Wang3Qian Zhang4Sisi Pu5Xin Ma6Jinglei Wang7Yangyang Pan8College of Veterinary Medicine, Gansu Agricultural UniversityCollege of Veterinary Medicine, Gansu Agricultural UniversityCollege of Veterinary Medicine, Gansu Agricultural UniversityCollege of Veterinary Medicine, Gansu Agricultural UniversityCollege of Veterinary Medicine, Gansu Agricultural UniversityCollege of Veterinary Medicine, Gansu Agricultural UniversityCollege of Veterinary Medicine, Gansu Agricultural UniversityCollege of Veterinary Medicine, Gansu Agricultural UniversityCollege of Veterinary Medicine, Gansu Agricultural UniversityAbstract Introduction This study aimed to investigate the microbial characteristics of yak uteri collected using intrauterine cotton swabs (CS) during different reproductive stages and the correlation of these microbial characteristics with reproductive status. Methods We used a macrogenomic approach to analyze the functional aspects of different microorganisms in samples collected during the pre-estrus, estrus, late estrus, and diestrus stages. Results The results revealed the presence of 1293 microbial genera and 3401 microbial species in the uteri of yaks at different reproductive stages. The dominant bacterial species varied across the different periods, with Micrococcus and Proteus being dominant during pre-estrus; Pseudomonas, Clostridium, Flavobacterium, Bacillus, and Staphylococcus during estrus; Acinetobacter, Bacillus and Proteus during late estrus; and Pseudomonas, Escherichia coli, and Proteus during diestrus. Discussion The primary functions of these bacteria are enriched in various metabolic pathways, including carbohydrate and amino acid metabolism, intracellular transport and secretion, post-translational protein modification, and drug resistance. These findings suggest that the microbial diversity in the uterus of yaks plays a crucial role in reproductive regulation and can help prevent reproductive tract-related diseases.https://doi.org/10.1186/s12917-023-03845-4Microbial characteristicsUterusYakEstrous cycleReproductive health |
| spellingShingle | Rui Wang Meng Wang Qiaoying Zeng Libin Wang Qian Zhang Sisi Pu Xin Ma Jinglei Wang Yangyang Pan Correlation between microbial characteristics and reproductive status of the yak uterus based on macrogenomic analysis BMC Veterinary Research Microbial characteristics Uterus Yak Estrous cycle Reproductive health |
| title | Correlation between microbial characteristics and reproductive status of the yak uterus based on macrogenomic analysis |
| title_full | Correlation between microbial characteristics and reproductive status of the yak uterus based on macrogenomic analysis |
| title_fullStr | Correlation between microbial characteristics and reproductive status of the yak uterus based on macrogenomic analysis |
| title_full_unstemmed | Correlation between microbial characteristics and reproductive status of the yak uterus based on macrogenomic analysis |
| title_short | Correlation between microbial characteristics and reproductive status of the yak uterus based on macrogenomic analysis |
| title_sort | correlation between microbial characteristics and reproductive status of the yak uterus based on macrogenomic analysis |
| topic | Microbial characteristics Uterus Yak Estrous cycle Reproductive health |
| url | https://doi.org/10.1186/s12917-023-03845-4 |
| work_keys_str_mv | AT ruiwang correlationbetweenmicrobialcharacteristicsandreproductivestatusoftheyakuterusbasedonmacrogenomicanalysis AT mengwang correlationbetweenmicrobialcharacteristicsandreproductivestatusoftheyakuterusbasedonmacrogenomicanalysis AT qiaoyingzeng correlationbetweenmicrobialcharacteristicsandreproductivestatusoftheyakuterusbasedonmacrogenomicanalysis AT libinwang correlationbetweenmicrobialcharacteristicsandreproductivestatusoftheyakuterusbasedonmacrogenomicanalysis AT qianzhang correlationbetweenmicrobialcharacteristicsandreproductivestatusoftheyakuterusbasedonmacrogenomicanalysis AT sisipu correlationbetweenmicrobialcharacteristicsandreproductivestatusoftheyakuterusbasedonmacrogenomicanalysis AT xinma correlationbetweenmicrobialcharacteristicsandreproductivestatusoftheyakuterusbasedonmacrogenomicanalysis AT jingleiwang correlationbetweenmicrobialcharacteristicsandreproductivestatusoftheyakuterusbasedonmacrogenomicanalysis AT yangyangpan correlationbetweenmicrobialcharacteristicsandreproductivestatusoftheyakuterusbasedonmacrogenomicanalysis |