Administration of Δ9‐Tetrahydrocannabinol (THC) Post‐Staphylococcal Enterotoxin B Exposure Protects Mice From Acute Respiratory Distress Syndrome and Toxicity

Administration of Δ9‐Tetrahydrocannabinol (THC) Post‐Staphylococcal Enterotoxin B Exposure Protects Mice From Acute Respiratory Distress Syndrome and Toxicity

Acute Respiratory Distress Syndrome (ARDS) is a life-threatening complication that can ensue following Staphylococcus aureus infection. The enterotoxin produced by these bacteria (SEB) acts as a superantigen thereby activating a large proportion of T cells leading to cytokine storm and severe lung i...

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Bibliographic Details
Main Authors: Amira Mohammed, Hasan Alghetaa, Muthanna Sultan, Narendra P. Singh, Prakash Nagarkatti, Mitzi Nagarkatti
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
acute respiratory distress syndrome
Δ9-Tetrahydrocannabinol (THC)
Staphylococcal enterotoxin B (SEB)
CB2 receptor
miR-34a
microRNA
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00893/full

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