Integrative multiomics evaluation reveals the importance of pseudouridine synthases in hepatocellular carcinoma

Integrative multiomics evaluation reveals the importance of pseudouridine synthases in hepatocellular carcinoma

Background: The pseudouridine synthases (PUSs) have been reported to be associated with cancers. However, their involvement in hepatocellular carcinoma (HCC) has not been well documented. Here, we assess the roles of PUSs in HCC.Methods: RNA sequencing data of TCGA-LIHC and LIRI-JP were downloaded f...

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Bibliographic Details
Main Authors: Zhipeng Jin, Mengying Song, Jianping Wang, Wenjing Zhu, Dongxu Sun, Huayuan Liu, Guangjun Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
pseudouridine synthase
HCC
biomarker
tumor microenvironment
multiomics data
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.944681/full

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