Biological Properties and Biomedical Applications of Pectin and Pectin-Based Composites: A Review

Pectin has recently drawn much attention in biomedical applications due to its distinctive chemical and biological properties. Polymers like pectin with cell-instructive properties are attractive natural biomaterials for tissue repair and regeneration. In addition, bioactive pectin and pectin-based...

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Main Author: Naznin Sultana
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/24/7974
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author Naznin Sultana
author_facet Naznin Sultana
author_sort Naznin Sultana
collection DOAJ
description Pectin has recently drawn much attention in biomedical applications due to its distinctive chemical and biological properties. Polymers like pectin with cell-instructive properties are attractive natural biomaterials for tissue repair and regeneration. In addition, bioactive pectin and pectin-based composites exhibit improved characteristics to deliver active molecules. Pectin and pectin-based composites serve as interactive matrices or scaffolds by stimulating cell adhesion and cell proliferation and enhancing tissue remodeling by forming an extracellular matrix in vivo. Several bioactive properties, such as immunoregulatory, antibacterial, anti-inflammatory, anti-tumor, and antioxidant activities, contribute to the pectin’s and pectin-based composite’s enhanced applications in tissue engineering and drug delivery systems. Tissue engineering scaffolds containing pectin and pectin-based conjugates or composites demonstrate essential features such as nontoxicity, tunable mechanical properties, biodegradability, and suitable surface properties. The design and fabrication of pectic composites are versatile for tissue engineering and drug delivery applications. This article reviews the promising characteristics of pectin or pectic polysaccharides and pectin-based composites and highlights their potential biomedical applications, focusing on drug delivery and tissue engineering.
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spelling doaj.art-be4666cf13ac4208b6937287da9ac74e2023-12-22T14:27:15ZengMDPI AGMolecules1420-30492023-12-012824797410.3390/molecules28247974Biological Properties and Biomedical Applications of Pectin and Pectin-Based Composites: A ReviewNaznin Sultana0Texas Undergraduate Medical Academy, Prairie View A&M University, Prairie View, TX 77446, USAPectin has recently drawn much attention in biomedical applications due to its distinctive chemical and biological properties. Polymers like pectin with cell-instructive properties are attractive natural biomaterials for tissue repair and regeneration. In addition, bioactive pectin and pectin-based composites exhibit improved characteristics to deliver active molecules. Pectin and pectin-based composites serve as interactive matrices or scaffolds by stimulating cell adhesion and cell proliferation and enhancing tissue remodeling by forming an extracellular matrix in vivo. Several bioactive properties, such as immunoregulatory, antibacterial, anti-inflammatory, anti-tumor, and antioxidant activities, contribute to the pectin’s and pectin-based composite’s enhanced applications in tissue engineering and drug delivery systems. Tissue engineering scaffolds containing pectin and pectin-based conjugates or composites demonstrate essential features such as nontoxicity, tunable mechanical properties, biodegradability, and suitable surface properties. The design and fabrication of pectic composites are versatile for tissue engineering and drug delivery applications. This article reviews the promising characteristics of pectin or pectic polysaccharides and pectin-based composites and highlights their potential biomedical applications, focusing on drug delivery and tissue engineering.https://www.mdpi.com/1420-3049/28/24/7974pectintissue engineeringdrug deliverycompositesbiomedical applications
spellingShingle Naznin Sultana
Biological Properties and Biomedical Applications of Pectin and Pectin-Based Composites: A Review
Molecules
pectin
tissue engineering
drug delivery
composites
biomedical applications
title Biological Properties and Biomedical Applications of Pectin and Pectin-Based Composites: A Review
title_full Biological Properties and Biomedical Applications of Pectin and Pectin-Based Composites: A Review
title_fullStr Biological Properties and Biomedical Applications of Pectin and Pectin-Based Composites: A Review
title_full_unstemmed Biological Properties and Biomedical Applications of Pectin and Pectin-Based Composites: A Review
title_short Biological Properties and Biomedical Applications of Pectin and Pectin-Based Composites: A Review
title_sort biological properties and biomedical applications of pectin and pectin based composites a review
topic pectin
tissue engineering
drug delivery
composites
biomedical applications
url https://www.mdpi.com/1420-3049/28/24/7974
work_keys_str_mv AT nazninsultana biologicalpropertiesandbiomedicalapplicationsofpectinandpectinbasedcompositesareview