tRNA synthetase counteracts c-Myc to develop functional vasculature

tRNA synthetase counteracts c-Myc to develop functional vasculature

Recent studies suggested an essential role for seryl-tRNA synthetase (SerRS) in vascular development. This role is specific to SerRS among all tRNA synthetases and is independent of its well-known aminoacylation function in protein synthesis. A unique nucleus-directing domain, added at the invertebr...

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Bibliographic Details
Main Authors: Yi Shi, Xiaoling Xu, Qian Zhang, Guangsen Fu, Zhongying Mo, George S Wang, Shuji Kishi, Xiang-Lei Yang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-06-01
Series:eLife
Subjects:
seryl-tRNA synthetase
c-Myc
VEGFA
SIRT2
angiogenesis
vasculature
Online Access:https://elifesciences.org/articles/02349

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