Clinical profile of young Indian women presenting with acute coronary syndrome

Introduction: Coronary artery disease is an important public health issue in India. Over the last few decades, several studies have led to an understanding of the disease with respect to Indian population. However, lacunae still exist in several aspects of this burning health issue. There is a lack...

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Main Authors: U M Nagamalesh, T Abhinay, K C Karthik Naidu, N Ambujam, Anupama V Hegde, V S Prakash
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Journal of Clinical and Preventive Cardiology
Subjects:
Online Access:http://www.jcpconline.org/article.asp?issn=2250-3528;year=2018;volume=7;issue=3;spage=106;epage=110;aulast=Nagamalesh
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author U M Nagamalesh
T Abhinay
K C Karthik Naidu
N Ambujam
Anupama V Hegde
V S Prakash
author_facet U M Nagamalesh
T Abhinay
K C Karthik Naidu
N Ambujam
Anupama V Hegde
V S Prakash
author_sort U M Nagamalesh
collection DOAJ
description Introduction: Coronary artery disease is an important public health issue in India. Over the last few decades, several studies have led to an understanding of the disease with respect to Indian population. However, lacunae still exist in several aspects of this burning health issue. There is a lack of data on acute coronary syndrome (ACS) in the young Indian population. Our study targeted an important subgroup of Indian population which is the young Indian women. In this study, we present a brief overview of the clinical and laboratory characteristics of young Indian women who presented in our Institute with ACS. Methods: A total of 63 female patients aged ≤45 years with a diagnosis of ACS after satisfying inclusion-exclusion criteria were chosen for the study. Baseline demographics, laboratory investigations, electrocardiogram, echocardiographic assessment, and coronary angiogram with subsequent treatment approach and outcomes were recorded. Results: Dyslipidemia was the most common prevalent risk factors among the study patients, while diabetes and hypertension were other common risk factors noted. Among 63 patients admitted with ACS, 77% (n = 21) received primary percutaneous coronary intervention (PCI) and 11.1% (n = 7) received thrombolytic therapy. The average duration of hospital stay was 4 ± 1 day. Conclusion: It was observed that dyslipidemia was major risk factor for ACS among young Indian woman included in our study. Other risk factors included diabetes mellitus and hypertension. Chest pain (95.2%) was the most common complaint. In 76% cases, the coronary angiogram revealed single vessel disease with left anterior descending coronary artery being the culprit vessel in 69.8% cases. Majority of the participants had preserved left ventricular function at the time of discharge. Nearly 85% of our patients received PCI as the revascularization strategy of choice.
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spelling doaj.art-be46d42aca244786b8bc1bd7815d88d82022-12-21T20:04:12ZengWolters Kluwer Medknow PublicationsJournal of Clinical and Preventive Cardiology2250-35282018-01-017310611010.4103/JCPC.JCPC_48_17Clinical profile of young Indian women presenting with acute coronary syndromeU M NagamaleshT AbhinayK C Karthik NaiduN AmbujamAnupama V HegdeV S PrakashIntroduction: Coronary artery disease is an important public health issue in India. Over the last few decades, several studies have led to an understanding of the disease with respect to Indian population. However, lacunae still exist in several aspects of this burning health issue. There is a lack of data on acute coronary syndrome (ACS) in the young Indian population. Our study targeted an important subgroup of Indian population which is the young Indian women. In this study, we present a brief overview of the clinical and laboratory characteristics of young Indian women who presented in our Institute with ACS. Methods: A total of 63 female patients aged ≤45 years with a diagnosis of ACS after satisfying inclusion-exclusion criteria were chosen for the study. Baseline demographics, laboratory investigations, electrocardiogram, echocardiographic assessment, and coronary angiogram with subsequent treatment approach and outcomes were recorded. Results: Dyslipidemia was the most common prevalent risk factors among the study patients, while diabetes and hypertension were other common risk factors noted. Among 63 patients admitted with ACS, 77% (n = 21) received primary percutaneous coronary intervention (PCI) and 11.1% (n = 7) received thrombolytic therapy. The average duration of hospital stay was 4 ± 1 day. Conclusion: It was observed that dyslipidemia was major risk factor for ACS among young Indian woman included in our study. Other risk factors included diabetes mellitus and hypertension. Chest pain (95.2%) was the most common complaint. In 76% cases, the coronary angiogram revealed single vessel disease with left anterior descending coronary artery being the culprit vessel in 69.8% cases. Majority of the participants had preserved left ventricular function at the time of discharge. Nearly 85% of our patients received PCI as the revascularization strategy of choice.http://www.jcpconline.org/article.asp?issn=2250-3528;year=2018;volume=7;issue=3;spage=106;epage=110;aulast=NagamaleshAcute coronary syndromeacute coronary syndrome in young womenmyocardial infarctionpercutaneous coronary intervention
spellingShingle U M Nagamalesh
T Abhinay
K C Karthik Naidu
N Ambujam
Anupama V Hegde
V S Prakash
Clinical profile of young Indian women presenting with acute coronary syndrome
Journal of Clinical and Preventive Cardiology
Acute coronary syndrome
acute coronary syndrome in young women
myocardial infarction
percutaneous coronary intervention
title Clinical profile of young Indian women presenting with acute coronary syndrome
title_full Clinical profile of young Indian women presenting with acute coronary syndrome
title_fullStr Clinical profile of young Indian women presenting with acute coronary syndrome
title_full_unstemmed Clinical profile of young Indian women presenting with acute coronary syndrome
title_short Clinical profile of young Indian women presenting with acute coronary syndrome
title_sort clinical profile of young indian women presenting with acute coronary syndrome
topic Acute coronary syndrome
acute coronary syndrome in young women
myocardial infarction
percutaneous coronary intervention
url http://www.jcpconline.org/article.asp?issn=2250-3528;year=2018;volume=7;issue=3;spage=106;epage=110;aulast=Nagamalesh
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