Psychosocially-Assisted Pharmacological Treatment of Opioid Dependent Adults: A Systematic Review
Background: Opioid dependence is a conundrum that significantly contributes to global mortality, crimes, and transmission of diseases such as hepatitis (B and C), human immunodeficiency virus and perhaps, coronavirus disease 2019 (COVID-19). There are contradictory findings on the efficacy of psych...
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| Format: | Article |
| Language: | English |
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Nigerian Medical Association, Akwa Ibom State Branch
2022-09-01
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| Series: | Ibom Medical Journal |
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| Online Access: | https://ibommedicaljournal.org/index.php/imjhome/article/view/264 |
| _version_ | 1797271901683318784 |
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| author | Wayah SB Waziri PM Onyebuchi CM Yahaya G Chindo BA |
| author_facet | Wayah SB Waziri PM Onyebuchi CM Yahaya G Chindo BA |
| author_sort | Wayah SB |
| collection | DOAJ |
| description |
Background: Opioid dependence is a conundrum that significantly contributes to global mortality, crimes, and transmission of diseases such as hepatitis (B and C), human immunodeficiency virus and perhaps, coronavirus disease 2019 (COVID-19). There are contradictory findings on the efficacy of psychosocially-assisted pharmacological treatment of opioid dependence in adults.
Objective: The overall objective of this research is to investigate if psychosocially-assisted pharmacological therapy has significantly better effect than pharmacological therapy with regards treatment outcomes of opioid dependent adults.
Methods: All methods employed in this study are in conformity with the preferred reporting items for systematic reviews and meta-analysis (PRISMA) framework for systematic review which involve identification, screening, eligibility and inclusion. This systematic review involved PubMed literature search on randomized controlled trials published between 1st January 2015 to 1st October 2021.
Results: PubMed search yielded 5,216 articles which were screened using inclusion and exclusion criteria resulting in 19 articled being retained for data extraction. Of the 19 articles used in this study, 13 (68.4%) articles having a combined sample size of 1,928 (60.6%) showed that addition of psychosocial intervention to pharmacotherapy significantly improved abstinence from opioid abuse.
Conclusion: The outcome of evaluation of the overall evidences presented in the 19 articles used in this study is that psychosocially-assisted pharmacological therapy is significantly better than pharmacological treatment with respect to enhancement of abstinence from opioid abuse among opioid-dependent adults. Additionally, this study has provided specific combinations of psychosocial and pharmacological treatment that can produce significant beneficial effect on opioid abstinence. The huge downturn in randomized controlled trials on treatment of opioid dependence among adults has been highlighted in this study.
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| first_indexed | 2024-03-07T14:16:50Z |
| format | Article |
| id | doaj.art-be47437a165e4a9f99d91227d60c1f6c |
| institution | Directory Open Access Journal |
| issn | 1597-7188 2735-9964 |
| language | English |
| last_indexed | 2024-03-07T14:16:50Z |
| publishDate | 2022-09-01 |
| publisher | Nigerian Medical Association, Akwa Ibom State Branch |
| record_format | Article |
| series | Ibom Medical Journal |
| spelling | doaj.art-be47437a165e4a9f99d91227d60c1f6c2024-03-06T11:55:43ZengNigerian Medical Association, Akwa Ibom State BranchIbom Medical Journal1597-71882735-99642022-09-0115310.61386/imj.v15i3.264Psychosocially-Assisted Pharmacological Treatment of Opioid Dependent Adults: A Systematic ReviewWayah SB0Waziri PM1Onyebuchi CM2Yahaya G3Chindo BA4Department of Biochemistry, Faculty of Science, Kaduna State University, NigeriaDepartment of Biochemistry, Faculty of Science, Kaduna State University, NigeriaDepartment of Nursing Science, Faculty of Applied Sciences, University of Sunderland, United KingdomDepartment of Biotechnology, Faculty of Health and Life Sciences, Coventry University, United KingdomDepartment of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Kaduna State University, Kaduna, Nigeria Background: Opioid dependence is a conundrum that significantly contributes to global mortality, crimes, and transmission of diseases such as hepatitis (B and C), human immunodeficiency virus and perhaps, coronavirus disease 2019 (COVID-19). There are contradictory findings on the efficacy of psychosocially-assisted pharmacological treatment of opioid dependence in adults. Objective: The overall objective of this research is to investigate if psychosocially-assisted pharmacological therapy has significantly better effect than pharmacological therapy with regards treatment outcomes of opioid dependent adults. Methods: All methods employed in this study are in conformity with the preferred reporting items for systematic reviews and meta-analysis (PRISMA) framework for systematic review which involve identification, screening, eligibility and inclusion. This systematic review involved PubMed literature search on randomized controlled trials published between 1st January 2015 to 1st October 2021. Results: PubMed search yielded 5,216 articles which were screened using inclusion and exclusion criteria resulting in 19 articled being retained for data extraction. Of the 19 articles used in this study, 13 (68.4%) articles having a combined sample size of 1,928 (60.6%) showed that addition of psychosocial intervention to pharmacotherapy significantly improved abstinence from opioid abuse. Conclusion: The outcome of evaluation of the overall evidences presented in the 19 articles used in this study is that psychosocially-assisted pharmacological therapy is significantly better than pharmacological treatment with respect to enhancement of abstinence from opioid abuse among opioid-dependent adults. Additionally, this study has provided specific combinations of psychosocial and pharmacological treatment that can produce significant beneficial effect on opioid abstinence. The huge downturn in randomized controlled trials on treatment of opioid dependence among adults has been highlighted in this study. https://ibommedicaljournal.org/index.php/imjhome/article/view/264Opioid dependenceAdultsPsychosocial interventionPharmacological treatmentPsychosocially-assisted pharmacological treatment |
| spellingShingle | Wayah SB Waziri PM Onyebuchi CM Yahaya G Chindo BA Psychosocially-Assisted Pharmacological Treatment of Opioid Dependent Adults: A Systematic Review Ibom Medical Journal Opioid dependence Adults Psychosocial intervention Pharmacological treatment Psychosocially-assisted pharmacological treatment |
| title | Psychosocially-Assisted Pharmacological Treatment of Opioid Dependent Adults: A Systematic Review |
| title_full | Psychosocially-Assisted Pharmacological Treatment of Opioid Dependent Adults: A Systematic Review |
| title_fullStr | Psychosocially-Assisted Pharmacological Treatment of Opioid Dependent Adults: A Systematic Review |
| title_full_unstemmed | Psychosocially-Assisted Pharmacological Treatment of Opioid Dependent Adults: A Systematic Review |
| title_short | Psychosocially-Assisted Pharmacological Treatment of Opioid Dependent Adults: A Systematic Review |
| title_sort | psychosocially assisted pharmacological treatment of opioid dependent adults a systematic review |
| topic | Opioid dependence Adults Psychosocial intervention Pharmacological treatment Psychosocially-assisted pharmacological treatment |
| url | https://ibommedicaljournal.org/index.php/imjhome/article/view/264 |
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