Knee muscle atrophy is a risk factor for development of knee osteoarthritis in a rat model

Knee muscle atrophy is a risk factor for development of knee osteoarthritis in a rat model

Objectives: The objective of this study was to investigate the effect of botulinum toxin type A (BTX-A)–induced quadriceps muscle atrophy on the cartilage and subchondral bone in an otherwise intact rat joint model. Methods: The rat right quadriceps muscle atrophy was established by intramuscular in...

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Bibliographic Details
Main Authors: Jichun Xu, Guorong She, Tao Gui, Huige Hou, Jieruo Li, Yuanfeng Chen, Zhengang Zha
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Journal of Orthopaedic Translation
Subjects:
Cartilage
Muscle atrophy
Osteoarthritis
Subchondral bone
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X19302153

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