Seborrheic dermatitis and its relationship with Malassezia spp
Seborrheic dermatitis (SD) is a chronic inflammatory disease that that is difficult to manage and with a high impact on the individual’s quality of life. Besides, it is a multifactorial entity that typically occurs as an inflammatory response to Malassezia species, along with specific triggers that...
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| Format: | Article |
| Language: | English |
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Asociación Colombiana de Infectología
2020-11-01
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| Series: | Infectio |
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| _version_ | 1818479792113057792 |
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| author | Manuel Alejandro Salamanca-Córdoba |
| author_facet | Manuel Alejandro Salamanca-Córdoba |
| author_sort | Manuel Alejandro Salamanca-Córdoba |
| collection | DOAJ |
| description | Seborrheic dermatitis (SD) is a chronic inflammatory disease that that is difficult to manage and with a high impact on the individual’s quality of life. Besides, it is a multifactorial entity that typically occurs as an inflammatory response to Malassezia species, along with specific triggers that contribute to its pathophysiology. Sin-ce the primary underlying pathogenic mechanisms include Malassezia proliferation and skin inflammation, the most common treatment includes topical antifungal keratolytics and anti-inflammatory agents. However, the consequences of eliminating the yeast population from the skin, the resistance profiles of Malassezia spp. and the effectivity among different groups of medications are unknown. Thus, in this review, we summarize the current knowledge on the disease ́s pathophysio-logy and the role of Malassezia sp. on it, as well as, the different antifungal treatment alternatives, including topical and oral treatment in the management of SD. |
| first_indexed | 2024-12-10T11:15:25Z |
| format | Article |
| id | doaj.art-be4b76ae7b01439dabbd10492c839f3c |
| institution | Directory Open Access Journal |
| issn | 0123-9392 |
| language | English |
| last_indexed | 2024-12-10T11:15:25Z |
| publishDate | 2020-11-01 |
| publisher | Asociación Colombiana de Infectología |
| record_format | Article |
| series | Infectio |
| spelling | doaj.art-be4b76ae7b01439dabbd10492c839f3c2022-12-22T01:51:13ZengAsociación Colombiana de InfectologíaInfectio0123-93922020-11-01252120129http://dx.doi.org/10.22354/in.v25i2.930Seborrheic dermatitis and its relationship with Malassezia sppManuel Alejandro Salamanca-Córdoba0Grupo de Investigación Celular y Molecular de Microorganismos Patógenos (CeMoP), Department of Biological Sciences, Universidad de los Andes, Bo-gotá, Cundinamarca, Colombia2 School of Medicine, Universidad de los Andes, Bogotá, Cundinamarca, ColombiSeborrheic dermatitis (SD) is a chronic inflammatory disease that that is difficult to manage and with a high impact on the individual’s quality of life. Besides, it is a multifactorial entity that typically occurs as an inflammatory response to Malassezia species, along with specific triggers that contribute to its pathophysiology. Sin-ce the primary underlying pathogenic mechanisms include Malassezia proliferation and skin inflammation, the most common treatment includes topical antifungal keratolytics and anti-inflammatory agents. However, the consequences of eliminating the yeast population from the skin, the resistance profiles of Malassezia spp. and the effectivity among different groups of medications are unknown. Thus, in this review, we summarize the current knowledge on the disease ́s pathophysio-logy and the role of Malassezia sp. on it, as well as, the different antifungal treatment alternatives, including topical and oral treatment in the management of SD.seborrheic dermatitismalasseziapathogenic roletreatment. |
| spellingShingle | Manuel Alejandro Salamanca-Córdoba Seborrheic dermatitis and its relationship with Malassezia spp Infectio seborrheic dermatitis malassezia pathogenic role treatment. |
| title | Seborrheic dermatitis and its relationship with Malassezia spp |
| title_full | Seborrheic dermatitis and its relationship with Malassezia spp |
| title_fullStr | Seborrheic dermatitis and its relationship with Malassezia spp |
| title_full_unstemmed | Seborrheic dermatitis and its relationship with Malassezia spp |
| title_short | Seborrheic dermatitis and its relationship with Malassezia spp |
| title_sort | seborrheic dermatitis and its relationship with malassezia spp |
| topic | seborrheic dermatitis malassezia pathogenic role treatment. |
| work_keys_str_mv | AT manuelalejandrosalamancacordoba seborrheicdermatitisanditsrelationshipwithmalasseziaspp |