Impact of Controlling Nutritional Status score on short-term outcomes after carotid endarterectomy: a retrospective cohort study
Background Malnutrition and impaired immune responses significantly affect the clinical outcomes of patients with atherosclerotic stenosis. The Controlling Nutritional Status (CONUT) score has recently been utilized to evaluate perioperative immunonutritional status. This study aimed to evaluate the...
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| Format: | Article |
| Language: | English |
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Yeungnam University College of Medicine, Yeungnam University Institute Medical Science
2023-07-01
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| Series: | Journal of Yeungnam Medical Science |
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| Online Access: | http://www.e-jyms.org/upload/pdf/jyms-2022-00507.pdf |
| _version_ | 1827890026210394112 |
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| author | Hee Won Son Gyeongseok Yu Seung Jun Lee Jimi Oh |
| author_facet | Hee Won Son Gyeongseok Yu Seung Jun Lee Jimi Oh |
| author_sort | Hee Won Son |
| collection | DOAJ |
| description | Background Malnutrition and impaired immune responses significantly affect the clinical outcomes of patients with atherosclerotic stenosis. The Controlling Nutritional Status (CONUT) score has recently been utilized to evaluate perioperative immunonutritional status. This study aimed to evaluate the relationship between immunonutritional status, indexed by CONUT score, and postoperative complications in patients undergoing carotid endarterectomy (CEA). Methods We retrospectively evaluated 188 patients who underwent elective CEA between January 2010 and December 2019. The preoperative CONUT score was calculated as the sum of the serum albumin concentration, total cholesterol level, and total lymphocyte count. The primary outcome was postoperative complications within 30 days after CEA, including major adverse cardiovascular events, pulmonary complications, stroke, renal failure, sepsis, wounds, and gastrointestinal complications. Cox proportional hazards regression analysis was used to estimate the factors associated with postoperative complications during the 30-day follow-up period. Results Twenty-five patients (13.3%) had at least one major complication. The incidence of postoperative complications was identified more frequently in the high CONUT group (12 of 27, 44.4% vs. 13 of 161, 8.1%; p<0.001). Multivariate analyses showed that a high preoperative CONUT score was independently associated with 30-day postoperative complications (hazard ratio, 5.98; 95% confidence interval, 2.56–13.97; p<0.001). Conclusion Our results showed that the CONUT score, a simple and readily available parameter using only objective laboratory values, is independently associated with early postoperative complications. |
| first_indexed | 2024-03-12T21:03:19Z |
| format | Article |
| id | doaj.art-be4bd53bb22a4645b7037d9be366f1fe |
| institution | Directory Open Access Journal |
| issn | 2799-8010 |
| language | English |
| last_indexed | 2024-03-12T21:03:19Z |
| publishDate | 2023-07-01 |
| publisher | Yeungnam University College of Medicine, Yeungnam University Institute Medical Science |
| record_format | Article |
| series | Journal of Yeungnam Medical Science |
| spelling | doaj.art-be4bd53bb22a4645b7037d9be366f1fe2023-07-31T00:03:40ZengYeungnam University College of Medicine, Yeungnam University Institute Medical ScienceJournal of Yeungnam Medical Science2799-80102023-07-0140325926710.12701/jyms.2022.005072749Impact of Controlling Nutritional Status score on short-term outcomes after carotid endarterectomy: a retrospective cohort studyHee Won Son0Gyeongseok Yu1Seung Jun Lee2Jimi Oh Department of Anesthesiology and Pain Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Anesthesiology and Pain Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea Department of Anesthesiology and Pain Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, KoreaBackground Malnutrition and impaired immune responses significantly affect the clinical outcomes of patients with atherosclerotic stenosis. The Controlling Nutritional Status (CONUT) score has recently been utilized to evaluate perioperative immunonutritional status. This study aimed to evaluate the relationship between immunonutritional status, indexed by CONUT score, and postoperative complications in patients undergoing carotid endarterectomy (CEA). Methods We retrospectively evaluated 188 patients who underwent elective CEA between January 2010 and December 2019. The preoperative CONUT score was calculated as the sum of the serum albumin concentration, total cholesterol level, and total lymphocyte count. The primary outcome was postoperative complications within 30 days after CEA, including major adverse cardiovascular events, pulmonary complications, stroke, renal failure, sepsis, wounds, and gastrointestinal complications. Cox proportional hazards regression analysis was used to estimate the factors associated with postoperative complications during the 30-day follow-up period. Results Twenty-five patients (13.3%) had at least one major complication. The incidence of postoperative complications was identified more frequently in the high CONUT group (12 of 27, 44.4% vs. 13 of 161, 8.1%; p<0.001). Multivariate analyses showed that a high preoperative CONUT score was independently associated with 30-day postoperative complications (hazard ratio, 5.98; 95% confidence interval, 2.56–13.97; p<0.001). Conclusion Our results showed that the CONUT score, a simple and readily available parameter using only objective laboratory values, is independently associated with early postoperative complications.http://www.e-jyms.org/upload/pdf/jyms-2022-00507.pdfcarotid endarterectomynutritional statuspostoperative complicationsprognosis |
| spellingShingle | Hee Won Son Gyeongseok Yu Seung Jun Lee Jimi Oh Impact of Controlling Nutritional Status score on short-term outcomes after carotid endarterectomy: a retrospective cohort study Journal of Yeungnam Medical Science carotid endarterectomy nutritional status postoperative complications prognosis |
| title | Impact of Controlling Nutritional Status score on short-term outcomes after carotid endarterectomy: a retrospective cohort study |
| title_full | Impact of Controlling Nutritional Status score on short-term outcomes after carotid endarterectomy: a retrospective cohort study |
| title_fullStr | Impact of Controlling Nutritional Status score on short-term outcomes after carotid endarterectomy: a retrospective cohort study |
| title_full_unstemmed | Impact of Controlling Nutritional Status score on short-term outcomes after carotid endarterectomy: a retrospective cohort study |
| title_short | Impact of Controlling Nutritional Status score on short-term outcomes after carotid endarterectomy: a retrospective cohort study |
| title_sort | impact of controlling nutritional status score on short term outcomes after carotid endarterectomy a retrospective cohort study |
| topic | carotid endarterectomy nutritional status postoperative complications prognosis |
| url | http://www.e-jyms.org/upload/pdf/jyms-2022-00507.pdf |
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