Pelviureteric junction obstruction in adults: A systematic review of the literature
Abstract. Background. Pelviureteric junction obstruction (PUJO) is a common urological disorder that can present at any stage of life. The underlying etiology in children has been well studied; however, a gap exists in the literature for the adult population. Herein, we performed a systematic review...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Health
2023-06-01
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| Series: | Current Urology |
| Online Access: | http://journals.lww.com/10.1097/CU9.0000000000000154 |
| _version_ | 1827805134140211200 |
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| author | Niall J. O'Sullivan Steven Anderson |
| author_facet | Niall J. O'Sullivan Steven Anderson |
| author_sort | Niall J. O'Sullivan |
| collection | DOAJ |
| description | Abstract. Background. Pelviureteric junction obstruction (PUJO) is a common urological disorder that can present at any stage of life. The underlying etiology in children has been well studied; however, a gap exists in the literature for the adult population. Herein, we performed a systematic review of the literature to evaluate the current evidence on the underlying etiologies of adult patients presenting with PUJO.
Materials and methods. Four electronic databases were searched for relevant studies assessing the underlying etiologies of pelviureteric junction obstruction in adults. Studies were assessed for eligibility based on predefined inclusion and exclusion criteria, and a critical appraisal of methodological quality and risk of bias was performed. Finally, qualitative and quantitative data analyses were performed.
Results. Twelve studies comprising a total of 513 patients with radiologically confirmed PUJO met the inclusion criteria and were included in our analysis. The most common finding was crossing vessels, which were observed in 50.5% of patients, followed by intrinsic ureteral stenosis (27.1%), adhesions (15.3%), and high insertion of the ureter (10.1%).
Conclusions. The underlying etiologies of PUJO in adults remain unclear. This study indicated that obstruction secondary to crossing vessels is the most common cause of obstruction in adults and occurs more frequently than in the pediatric population. |
| first_indexed | 2024-03-11T21:21:15Z |
| format | Article |
| id | doaj.art-be4c4e37a1684824bffedd56065a75aa |
| institution | Directory Open Access Journal |
| issn | 1661-7649 |
| language | English |
| last_indexed | 2024-03-11T21:21:15Z |
| publishDate | 2023-06-01 |
| publisher | Wolters Kluwer Health |
| record_format | Article |
| series | Current Urology |
| spelling | doaj.art-be4c4e37a1684824bffedd56065a75aa2023-09-28T07:07:38ZengWolters Kluwer HealthCurrent Urology1661-76492023-06-01172869110.1097/CU9.0000000000000154202306000-00004Pelviureteric junction obstruction in adults: A systematic review of the literatureNiall J. O'Sullivan0Steven Anderson1a Department of Urology, Tallaght University Hospital, Dublin, Irelandb Department of Urology, Beaumont Hospital, Dublin, IrelandAbstract. Background. Pelviureteric junction obstruction (PUJO) is a common urological disorder that can present at any stage of life. The underlying etiology in children has been well studied; however, a gap exists in the literature for the adult population. Herein, we performed a systematic review of the literature to evaluate the current evidence on the underlying etiologies of adult patients presenting with PUJO. Materials and methods. Four electronic databases were searched for relevant studies assessing the underlying etiologies of pelviureteric junction obstruction in adults. Studies were assessed for eligibility based on predefined inclusion and exclusion criteria, and a critical appraisal of methodological quality and risk of bias was performed. Finally, qualitative and quantitative data analyses were performed. Results. Twelve studies comprising a total of 513 patients with radiologically confirmed PUJO met the inclusion criteria and were included in our analysis. The most common finding was crossing vessels, which were observed in 50.5% of patients, followed by intrinsic ureteral stenosis (27.1%), adhesions (15.3%), and high insertion of the ureter (10.1%). Conclusions. The underlying etiologies of PUJO in adults remain unclear. This study indicated that obstruction secondary to crossing vessels is the most common cause of obstruction in adults and occurs more frequently than in the pediatric population.http://journals.lww.com/10.1097/CU9.0000000000000154 |
| spellingShingle | Niall J. O'Sullivan Steven Anderson Pelviureteric junction obstruction in adults: A systematic review of the literature Current Urology |
| title | Pelviureteric junction obstruction in adults: A systematic review of the literature |
| title_full | Pelviureteric junction obstruction in adults: A systematic review of the literature |
| title_fullStr | Pelviureteric junction obstruction in adults: A systematic review of the literature |
| title_full_unstemmed | Pelviureteric junction obstruction in adults: A systematic review of the literature |
| title_short | Pelviureteric junction obstruction in adults: A systematic review of the literature |
| title_sort | pelviureteric junction obstruction in adults a systematic review of the literature |
| url | http://journals.lww.com/10.1097/CU9.0000000000000154 |
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