A Septin Cytoskeleton-Targeting Small Molecule, Forchlorfenuron, Inhibits Epithelial Migration via Septin-Independent Perturbation of Cellular Signaling
Septins are GTP-binding proteins that self-assemble into high-order cytoskeletal structures, filaments, and rings. The septin cytoskeleton has a number of cellular functions, including regulation of cytokinesis, cell migration, vesicle trafficking, and receptor signaling. A plant cytokinin, forchlor...
Main Authors: | Lei Sun, Xuelei Cao, Susana Lechuga, Alex Feygin, Nayden G. Naydenov, Andrei I. Ivanov |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-12-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/1/84 |
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