Prevalence of non-fermenting Gram-negative bacilli and their in vitro susceptibility pattern at a tertiary care teaching hospital
Background: Aerobic non-fermenting Gram-negative bacilli (NFGNB) once considered as contaminants now associated with life-threatening infections and emerging as multi drug resistant nosocomial pathogens. Aim: Isolation and identification of NFGNB in all the clinical samples and to determine antibiot...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2014-01-01
|
| Series: | Journal of the Scientific Society |
| Subjects: | |
| Online Access: | http://www.jscisociety.com/article.asp?issn=0974-5009;year=2014;volume=41;issue=3;spage=162;epage=166;aulast=Benachinmardi |
| _version_ | 1818850095582412800 |
|---|---|
| author | Kirtilaxmi K Benachinmardi M Padmavathy J Malini B V Naveneeth |
| author_facet | Kirtilaxmi K Benachinmardi M Padmavathy J Malini B V Naveneeth |
| author_sort | Kirtilaxmi K Benachinmardi |
| collection | DOAJ |
| description | Background: Aerobic non-fermenting Gram-negative bacilli (NFGNB) once considered as contaminants now associated with life-threatening infections and emerging as multi drug resistant nosocomial pathogens. Aim: Isolation and identification of NFGNB in all the clinical samples and to determine antibiotic susceptibility pattern of the isolated NFGNB. Materials and Methods: This study has been conducted in the Department of Microbiology at a tertiary care teaching hospital over a period of 2 months from September to October 2013. NFGNB were isolated and identified from clinical specimens by standard procedure and antibiotic sensitivity test was performed. Results: NFGNB isolation rate in the present study was 3.58%. Male to female ratio was 2.125. Pus was the most common specimen (21%) followed by tracheal aspirate (17%). Pseudomonas aeruginosa was the most common isolate (60%) followed by Acinetobacter baumannii (22%) and Acinetobacter lwoffii (12%). P. aeruginosa has shown good sensitivity to amikacin (83.3%), imipenem (80%) and piperacillin-tazobactam (73.3%) whereas A. baumannii showed multidrug resistance. Conclusion: It is necessary to identify NFGNB and to monitor their susceptibility pattern to guide the clinician for better care and management of patients. NFGNB are now emerging as organisms of nosocomial infections. Hence, antibiotic sensitivity testing and infection control measures are needed to prevent the emergence and spread of multi drug resistant NFGNB in health care settings. |
| first_indexed | 2024-12-19T06:43:41Z |
| format | Article |
| id | doaj.art-be50c647bcfa41a48e38e08f5684dec5 |
| institution | Directory Open Access Journal |
| issn | 0974-5009 |
| language | English |
| last_indexed | 2024-12-19T06:43:41Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of the Scientific Society |
| spelling | doaj.art-be50c647bcfa41a48e38e08f5684dec52022-12-21T20:31:58ZengWolters Kluwer Medknow PublicationsJournal of the Scientific Society0974-50092014-01-0141316216610.4103/0974-5009.141204Prevalence of non-fermenting Gram-negative bacilli and their in vitro susceptibility pattern at a tertiary care teaching hospitalKirtilaxmi K BenachinmardiM PadmavathyJ MaliniB V NaveneethBackground: Aerobic non-fermenting Gram-negative bacilli (NFGNB) once considered as contaminants now associated with life-threatening infections and emerging as multi drug resistant nosocomial pathogens. Aim: Isolation and identification of NFGNB in all the clinical samples and to determine antibiotic susceptibility pattern of the isolated NFGNB. Materials and Methods: This study has been conducted in the Department of Microbiology at a tertiary care teaching hospital over a period of 2 months from September to October 2013. NFGNB were isolated and identified from clinical specimens by standard procedure and antibiotic sensitivity test was performed. Results: NFGNB isolation rate in the present study was 3.58%. Male to female ratio was 2.125. Pus was the most common specimen (21%) followed by tracheal aspirate (17%). Pseudomonas aeruginosa was the most common isolate (60%) followed by Acinetobacter baumannii (22%) and Acinetobacter lwoffii (12%). P. aeruginosa has shown good sensitivity to amikacin (83.3%), imipenem (80%) and piperacillin-tazobactam (73.3%) whereas A. baumannii showed multidrug resistance. Conclusion: It is necessary to identify NFGNB and to monitor their susceptibility pattern to guide the clinician for better care and management of patients. NFGNB are now emerging as organisms of nosocomial infections. Hence, antibiotic sensitivity testing and infection control measures are needed to prevent the emergence and spread of multi drug resistant NFGNB in health care settings.http://www.jscisociety.com/article.asp?issn=0974-5009;year=2014;volume=41;issue=3;spage=162;epage=166;aulast=BenachinmardiAcinetobacter baumanniiAcinetobacter lwoffiinon-fermenting Gram-negative bacilliPseudomonas aeruginosa |
| spellingShingle | Kirtilaxmi K Benachinmardi M Padmavathy J Malini B V Naveneeth Prevalence of non-fermenting Gram-negative bacilli and their in vitro susceptibility pattern at a tertiary care teaching hospital Journal of the Scientific Society Acinetobacter baumannii Acinetobacter lwoffii non-fermenting Gram-negative bacilli Pseudomonas aeruginosa |
| title | Prevalence of non-fermenting Gram-negative bacilli and their in vitro susceptibility pattern at a tertiary care teaching hospital |
| title_full | Prevalence of non-fermenting Gram-negative bacilli and their in vitro susceptibility pattern at a tertiary care teaching hospital |
| title_fullStr | Prevalence of non-fermenting Gram-negative bacilli and their in vitro susceptibility pattern at a tertiary care teaching hospital |
| title_full_unstemmed | Prevalence of non-fermenting Gram-negative bacilli and their in vitro susceptibility pattern at a tertiary care teaching hospital |
| title_short | Prevalence of non-fermenting Gram-negative bacilli and their in vitro susceptibility pattern at a tertiary care teaching hospital |
| title_sort | prevalence of non fermenting gram negative bacilli and their in vitro susceptibility pattern at a tertiary care teaching hospital |
| topic | Acinetobacter baumannii Acinetobacter lwoffii non-fermenting Gram-negative bacilli Pseudomonas aeruginosa |
| url | http://www.jscisociety.com/article.asp?issn=0974-5009;year=2014;volume=41;issue=3;spage=162;epage=166;aulast=Benachinmardi |
| work_keys_str_mv | AT kirtilaxmikbenachinmardi prevalenceofnonfermentinggramnegativebacilliandtheirinvitrosusceptibilitypatternatatertiarycareteachinghospital AT mpadmavathy prevalenceofnonfermentinggramnegativebacilliandtheirinvitrosusceptibilitypatternatatertiarycareteachinghospital AT jmalini prevalenceofnonfermentinggramnegativebacilliandtheirinvitrosusceptibilitypatternatatertiarycareteachinghospital AT bvnaveneeth prevalenceofnonfermentinggramnegativebacilliandtheirinvitrosusceptibilitypatternatatertiarycareteachinghospital |