Effects of Air Pollution and Other Environmental Exposures on Estimates of Severe Influenza Illness, Washington, USA
Ecologic models of influenza burden may be confounded by other exposures that share winter seasonality. We evaluated the effects of air pollution and other environmental exposures in ecologic models estimating influenza-associated hospitalizations. We linked hospitalization data, viral surveillance,...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2020-05-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/26/5/19-0599_article |
| _version_ | 1818943150238990336 |
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| author | Ranjani Somayaji Moni B. Neradilek Adam A. Szpiro Kathryn H. Lofy Michael L. Jackson Christopher H. Goss Jeffrey S. Duchin Kathleen M. Neuzil Justin R. Ortiz |
| author_facet | Ranjani Somayaji Moni B. Neradilek Adam A. Szpiro Kathryn H. Lofy Michael L. Jackson Christopher H. Goss Jeffrey S. Duchin Kathleen M. Neuzil Justin R. Ortiz |
| author_sort | Ranjani Somayaji |
| collection | DOAJ |
| description | Ecologic models of influenza burden may be confounded by other exposures that share winter seasonality. We evaluated the effects of air pollution and other environmental exposures in ecologic models estimating influenza-associated hospitalizations. We linked hospitalization data, viral surveillance, and environmental data, including temperature, relative humidity, dew point, and fine particulate matter for 3 counties in Washington, USA, for 2001–2012. We used negative binomial regression models to estimate the incidence of influenza-associated respiratory and circulatory (RC) hospitalizations and to assess the effect of adjusting for environmental exposures on RC hospitalization estimates. The modeled overall incidence rate of influenza-associated RC hospitalizations was 31/100,000 person-years. The environmental parameters were statistically associated with RC hospitalizations but did not appreciably affect the event rate estimates. Modeled influenza-associated RC hospitalization rates were similar to published estimates, and inclusion of environmental covariates in the model did not have a clinically important effect on severe influenza estimates. |
| first_indexed | 2024-12-20T07:22:45Z |
| format | Article |
| id | doaj.art-be524fe72d8244e2b47edd4124430944 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-20T07:22:45Z |
| publishDate | 2020-05-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-be524fe72d8244e2b47edd41244309442022-12-21T19:48:38ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592020-05-0126592092910.3201/eid2605.190599Effects of Air Pollution and Other Environmental Exposures on Estimates of Severe Influenza Illness, Washington, USARanjani SomayajiMoni B. NeradilekAdam A. SzpiroKathryn H. LofyMichael L. JacksonChristopher H. GossJeffrey S. DuchinKathleen M. NeuzilJustin R. OrtizEcologic models of influenza burden may be confounded by other exposures that share winter seasonality. We evaluated the effects of air pollution and other environmental exposures in ecologic models estimating influenza-associated hospitalizations. We linked hospitalization data, viral surveillance, and environmental data, including temperature, relative humidity, dew point, and fine particulate matter for 3 counties in Washington, USA, for 2001–2012. We used negative binomial regression models to estimate the incidence of influenza-associated respiratory and circulatory (RC) hospitalizations and to assess the effect of adjusting for environmental exposures on RC hospitalization estimates. The modeled overall incidence rate of influenza-associated RC hospitalizations was 31/100,000 person-years. The environmental parameters were statistically associated with RC hospitalizations but did not appreciably affect the event rate estimates. Modeled influenza-associated RC hospitalization rates were similar to published estimates, and inclusion of environmental covariates in the model did not have a clinically important effect on severe influenza estimates.https://wwwnc.cdc.gov/eid/article/26/5/19-0599_articleinfluenzahospitalizationair pollutionepidemiologyrespiratory syncytial virusRSV |
| spellingShingle | Ranjani Somayaji Moni B. Neradilek Adam A. Szpiro Kathryn H. Lofy Michael L. Jackson Christopher H. Goss Jeffrey S. Duchin Kathleen M. Neuzil Justin R. Ortiz Effects of Air Pollution and Other Environmental Exposures on Estimates of Severe Influenza Illness, Washington, USA Emerging Infectious Diseases influenza hospitalization air pollution epidemiology respiratory syncytial virus RSV |
| title | Effects of Air Pollution and Other Environmental Exposures on Estimates of Severe Influenza Illness, Washington, USA |
| title_full | Effects of Air Pollution and Other Environmental Exposures on Estimates of Severe Influenza Illness, Washington, USA |
| title_fullStr | Effects of Air Pollution and Other Environmental Exposures on Estimates of Severe Influenza Illness, Washington, USA |
| title_full_unstemmed | Effects of Air Pollution and Other Environmental Exposures on Estimates of Severe Influenza Illness, Washington, USA |
| title_short | Effects of Air Pollution and Other Environmental Exposures on Estimates of Severe Influenza Illness, Washington, USA |
| title_sort | effects of air pollution and other environmental exposures on estimates of severe influenza illness washington usa |
| topic | influenza hospitalization air pollution epidemiology respiratory syncytial virus RSV |
| url | https://wwwnc.cdc.gov/eid/article/26/5/19-0599_article |
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