Analysis of carcinogenic risk and dynamics of population morbidity and mortality in the Irkutsk region due to malignant neoplasms

Morbidity and mortality caused by malignant neoplasms (MNs) is a priority challenge for health care. We analyzed some rough and standardized levels (oncological morbidity and mortality) over 2009–2018 based on official statistics. We ranked the RF regions as per the standardized morbidity level a...

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Main Authors: I.G. Zhdanova-Zaplesvichko, N.V. Efimova, D.F. Savinykh, М.F. Savchenkov
Format: Article
Language:English
Published: FBSI “Federal Scientific Center for Medical and Preventive Health Risk Management Technologies” 2023-09-01
Series:Analiz Riska Zdorovʹû
Subjects:
Online Access:https://journal.fcrisk.ru/eng/2023/3/4
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author I.G. Zhdanova-Zaplesvichko
N.V. Efimova
D.F. Savinykh
М.F. Savchenkov
author_facet I.G. Zhdanova-Zaplesvichko
N.V. Efimova
D.F. Savinykh
М.F. Savchenkov
author_sort I.G. Zhdanova-Zaplesvichko
collection DOAJ
description Morbidity and mortality caused by malignant neoplasms (MNs) is a priority challenge for health care. We analyzed some rough and standardized levels (oncological morbidity and mortality) over 2009–2018 based on official statistics. We ranked the RF regions as per the standardized morbidity level and established that the Irkutsk region took the 1st rank place among 85 RF regions as per it; it took the 16th rank place as per the ‘rough’ level. Morbidity and mortality levels that were higher in the Irkutsk region than the national average were established for such localizations as trachea, bronchi and lung cancer; prostate cancer; cervical cancer. The mortality to morbidity ratios were on average equal to 0.45 in the Irkutsk region and 0.49 in the RF as a whole; we identified a certain decrease in them, by 19.3 % and 20.0 % accordingly. We provided evidence of unacceptable individual carcinogenic chemical risk for people in cities with developed chemical industry and non-ferrous metallurgy. High carcinogenic radiation risks were caused by natural radon levels in soils. We calculated some prognostic morbidity and mortality levels: in 2021, the standardized morbidity level would be between 270.9 and 329.8 cases per 100 thousand people; the ‘rough’ level, between 372.7 and 532.4. The ‘rough’ mortality level would be between 220 and 230 cases per 100 thousand people. We determined some priority tasks for future research aimed at identifying adverse effects produced by environmental factors and lifestyle-related factors as well as some tasks related to developing relevant targeted activities aimed at eliminating and mitigating cancer-inducing exposures.
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spelling doaj.art-be54d9e8fc4849e2bacd44640e042f8b2023-11-08T09:28:27ZengFBSI “Federal Scientific Center for Medical and Preventive Health Risk Management Technologies”Analiz Riska Zdorovʹû2308-11552308-11632023-09-013394810.21668/health.risk/2023.3.04.engAnalysis of carcinogenic risk and dynamics of population morbidity and mortality in the Irkutsk region due to malignant neoplasmsI.G. Zhdanova-Zaplesvichko0N.V. Efimova1D.F. Savinykh2 М.F. Savchenkov3Federal Service for Surveillance over Consumer Rights Protection and Human Well-being, Irkutsk regional office, 8 Karla Marksa Str., Irkutsk, 664003, Russian Federation; Irkutsk State Medical Academy of Postgraduate Education – the branch of the Russian Medical Academy for Continuous Occupational Education, 100 Yubileinyi microdistrict, Irkutsk, 664049, Russian FederationEast-Siberian Institute of Medical and Ecological Research, 3 12a microdistrict, Angarsk, 665827, Russian FederationFederal Service for Surveillance over Consumer Rights Protection and Human Well-being, Irkutsk regional office, 8 Karla Marksa Str., Irkutsk, 664003, Russian FederationIrkutsk State Medical University, 1 Krasnogo Vosstaniya Str., Irkutsk, 664003, Russian FederationMorbidity and mortality caused by malignant neoplasms (MNs) is a priority challenge for health care. We analyzed some rough and standardized levels (oncological morbidity and mortality) over 2009–2018 based on official statistics. We ranked the RF regions as per the standardized morbidity level and established that the Irkutsk region took the 1st rank place among 85 RF regions as per it; it took the 16th rank place as per the ‘rough’ level. Morbidity and mortality levels that were higher in the Irkutsk region than the national average were established for such localizations as trachea, bronchi and lung cancer; prostate cancer; cervical cancer. The mortality to morbidity ratios were on average equal to 0.45 in the Irkutsk region and 0.49 in the RF as a whole; we identified a certain decrease in them, by 19.3 % and 20.0 % accordingly. We provided evidence of unacceptable individual carcinogenic chemical risk for people in cities with developed chemical industry and non-ferrous metallurgy. High carcinogenic radiation risks were caused by natural radon levels in soils. We calculated some prognostic morbidity and mortality levels: in 2021, the standardized morbidity level would be between 270.9 and 329.8 cases per 100 thousand people; the ‘rough’ level, between 372.7 and 532.4. The ‘rough’ mortality level would be between 220 and 230 cases per 100 thousand people. We determined some priority tasks for future research aimed at identifying adverse effects produced by environmental factors and lifestyle-related factors as well as some tasks related to developing relevant targeted activities aimed at eliminating and mitigating cancer-inducing exposures. https://journal.fcrisk.ru/eng/2023/3/4carcinogenic riskmorbiditymortalitymalignant neoplasmspopulationchemical factorradiation factorprognosis
spellingShingle I.G. Zhdanova-Zaplesvichko
N.V. Efimova
D.F. Savinykh
М.F. Savchenkov
Analysis of carcinogenic risk and dynamics of population morbidity and mortality in the Irkutsk region due to malignant neoplasms
Analiz Riska Zdorovʹû
carcinogenic risk
morbidity
mortality
malignant neoplasms
population
chemical factor
radiation factor
prognosis
title Analysis of carcinogenic risk and dynamics of population morbidity and mortality in the Irkutsk region due to malignant neoplasms
title_full Analysis of carcinogenic risk and dynamics of population morbidity and mortality in the Irkutsk region due to malignant neoplasms
title_fullStr Analysis of carcinogenic risk and dynamics of population morbidity and mortality in the Irkutsk region due to malignant neoplasms
title_full_unstemmed Analysis of carcinogenic risk and dynamics of population morbidity and mortality in the Irkutsk region due to malignant neoplasms
title_short Analysis of carcinogenic risk and dynamics of population morbidity and mortality in the Irkutsk region due to malignant neoplasms
title_sort analysis of carcinogenic risk and dynamics of population morbidity and mortality in the irkutsk region due to malignant neoplasms
topic carcinogenic risk
morbidity
mortality
malignant neoplasms
population
chemical factor
radiation factor
prognosis
url https://journal.fcrisk.ru/eng/2023/3/4
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AT dfsavinykh analysisofcarcinogenicriskanddynamicsofpopulationmorbidityandmortalityintheirkutskregionduetomalignantneoplasms
AT mfsavchenkov analysisofcarcinogenicriskanddynamicsofpopulationmorbidityandmortalityintheirkutskregionduetomalignantneoplasms