Treatment of relapsing multiple sclerosis in Hungary – consensus recommendation from the Hungarian neuroimmunology society
Abstract Multiple sclerosis (MS) may impact quality of life, careers and family plans of the affected individuals. The current treatments with disease modifying therapies aim to prevent people with MS (pwMS) from disability accumulation and progression. Different countries have different reimburseme...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-07-01
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| Series: | Orphanet Journal of Rare Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13023-023-02789-0 |
| _version_ | 1797784447870828544 |
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| author | Cecilia Rajda Csilla Rózsa Andrea Mike Gábor Lovas Zsolt Mezei Gábor Jakab Péter Ács Gábor Rum Magdolna Simó Zita Jobbágy Zita Bíró Anita Trauninger Piroska Imre Klotild Mátyás István Deme Zsolt Illés Tunde Csepany |
| author_facet | Cecilia Rajda Csilla Rózsa Andrea Mike Gábor Lovas Zsolt Mezei Gábor Jakab Péter Ács Gábor Rum Magdolna Simó Zita Jobbágy Zita Bíró Anita Trauninger Piroska Imre Klotild Mátyás István Deme Zsolt Illés Tunde Csepany |
| author_sort | Cecilia Rajda |
| collection | DOAJ |
| description | Abstract Multiple sclerosis (MS) may impact quality of life, careers and family plans of the affected individuals. The current treatments with disease modifying therapies aim to prevent people with MS (pwMS) from disability accumulation and progression. Different countries have different reimbursement policies resulting in inequalities in patient care among geographical regions. Access to anti-CD20 therapies for relapsing MS is restricted in Hungary because therapy of individual cases only is reimbursed. In the light of the latest research and national guidelines, 17 Hungarian MS experts agreed on 8 recommendations regarding relapsing pwMS using the Delphi round method. Strong agreement (> 80%) was achieved in all except one recommendation after three rounds, which generated a fourth Delphi round. The experts agreed on treatment initiation, switch, follow-up and discontinuation, as well as on special issues such as pregnancy, lactation, elderly population, and vaccination. Well-defined national consensus protocols may facilitate dialogue between policymakers and healthcare professionals and thus contribute to better patient care in the long run. |
| first_indexed | 2024-03-13T00:40:00Z |
| format | Article |
| id | doaj.art-be59c2447b67412d8c543f4314d3ae5c |
| institution | Directory Open Access Journal |
| issn | 1750-1172 |
| language | English |
| last_indexed | 2024-03-13T00:40:00Z |
| publishDate | 2023-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Orphanet Journal of Rare Diseases |
| spelling | doaj.art-be59c2447b67412d8c543f4314d3ae5c2023-07-09T11:24:55ZengBMCOrphanet Journal of Rare Diseases1750-11722023-07-011811810.1186/s13023-023-02789-0Treatment of relapsing multiple sclerosis in Hungary – consensus recommendation from the Hungarian neuroimmunology societyCecilia Rajda0Csilla Rózsa1Andrea Mike2Gábor Lovas3Zsolt Mezei4Gábor Jakab5Péter Ács6Gábor Rum7Magdolna Simó8Zita Jobbágy9Zita Bíró10Anita Trauninger11Piroska Imre12Klotild Mátyás13István Deme14Zsolt Illés15Tunde Csepany16Department of Neurology, Albert Szent-Györgyi Health Centre, University of SzegedDepartment of Neurology, Jahn Ferenc Teaching HospitalDepartment of Neurology, Szent Borbála HospitalDepartment of Neurology, Jahn Ferenc Teaching HospitalDepartment of Neurology, Faculty of Medicine, Semmelweis UniversityDepartment of Neurology, Uzsoki HospitalDepartment of Neurology, Medical School, University of PécsPetz Aladár Department of Neurology, County Teaching HospitalDepartment of Neurology, Faculty of Medicine, Semmelweis UniversityDepartment of Neurology, Bács-Kiskun County Teaching HospitalDepartment of Neurology, Flór Ferenc HospitalDepartment of Neurology, Medical School, University of PécsDepartment of Neurology, Csolnoky Ferenc HospitalDepartment of Neurology, Markhot Ferenc Teaching HospitalDepartment of Neurology, Kaposi Mór Teaching HospitalDepartment of Neurology, Odense University Hospital, Institute of Clinical Research, University of Southern DenmarkDepartment of Neurology, Faculty of Medicine, University of DebrecenAbstract Multiple sclerosis (MS) may impact quality of life, careers and family plans of the affected individuals. The current treatments with disease modifying therapies aim to prevent people with MS (pwMS) from disability accumulation and progression. Different countries have different reimbursement policies resulting in inequalities in patient care among geographical regions. Access to anti-CD20 therapies for relapsing MS is restricted in Hungary because therapy of individual cases only is reimbursed. In the light of the latest research and national guidelines, 17 Hungarian MS experts agreed on 8 recommendations regarding relapsing pwMS using the Delphi round method. Strong agreement (> 80%) was achieved in all except one recommendation after three rounds, which generated a fourth Delphi round. The experts agreed on treatment initiation, switch, follow-up and discontinuation, as well as on special issues such as pregnancy, lactation, elderly population, and vaccination. Well-defined national consensus protocols may facilitate dialogue between policymakers and healthcare professionals and thus contribute to better patient care in the long run.https://doi.org/10.1186/s13023-023-02789-0ConsensusMultiple sclerosisRecommendationTreatment |
| spellingShingle | Cecilia Rajda Csilla Rózsa Andrea Mike Gábor Lovas Zsolt Mezei Gábor Jakab Péter Ács Gábor Rum Magdolna Simó Zita Jobbágy Zita Bíró Anita Trauninger Piroska Imre Klotild Mátyás István Deme Zsolt Illés Tunde Csepany Treatment of relapsing multiple sclerosis in Hungary – consensus recommendation from the Hungarian neuroimmunology society Orphanet Journal of Rare Diseases Consensus Multiple sclerosis Recommendation Treatment |
| title | Treatment of relapsing multiple sclerosis in Hungary – consensus recommendation from the Hungarian neuroimmunology society |
| title_full | Treatment of relapsing multiple sclerosis in Hungary – consensus recommendation from the Hungarian neuroimmunology society |
| title_fullStr | Treatment of relapsing multiple sclerosis in Hungary – consensus recommendation from the Hungarian neuroimmunology society |
| title_full_unstemmed | Treatment of relapsing multiple sclerosis in Hungary – consensus recommendation from the Hungarian neuroimmunology society |
| title_short | Treatment of relapsing multiple sclerosis in Hungary – consensus recommendation from the Hungarian neuroimmunology society |
| title_sort | treatment of relapsing multiple sclerosis in hungary consensus recommendation from the hungarian neuroimmunology society |
| topic | Consensus Multiple sclerosis Recommendation Treatment |
| url | https://doi.org/10.1186/s13023-023-02789-0 |
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