Upregulation of Anti-Angiogenic miR-106b-3p Correlates Negatively with IGF-1 and Vascular Health Parameters in a Model of Subclinical Cardiovascular Disease: Study with Metformin Therapy

Upregulation of Anti-Angiogenic miR-106b-3p Correlates Negatively with IGF-1 and Vascular Health Parameters in a Model of Subclinical Cardiovascular Disease: Study with Metformin Therapy

Well-controlled type 1 diabetes mellitus (T1DM) is regarded as a model of subclinical cardiovascular disease (CVD), characterized by inflammation and adverse vascular health. However, the underlying mechanisms are not fully understood. We investigated insulin-like growth factor-1 (IGF-1) and IGF-bin...

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Bibliographic Details
Main Authors: Sherin Bakhashab, Josie O’Neill, Rosie Barber, Catherine Arden, Jolanta U. Weaver
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomedicines
Subjects:
IGF-1
IGFBP-3
miR-106b-3p
CFU-Hill colonies
subclinical CVD
metformin
Online Access:https://www.mdpi.com/2227-9059/12/1/171

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