The Regulation of Leptin, Leptin Receptor and Pro-opiomelanocortin Expression by N-3 PUFAs in Diet-Induced Obese Mice Is Not Related to the Methylation of Their Promoters

The Regulation of Leptin, Leptin Receptor and Pro-opiomelanocortin Expression by N-3 PUFAs in Diet-Induced Obese Mice Is Not Related to the Methylation of Their Promoters

<p>Abstract</p> <p>Background</p> <p>The expression of leptin is increased in obesity and inhibited by n-3 polyunsaturated fatty acids (n-3 PUFAs), but the underlying molecular mechanisms have not been firmly established.</p> <p>Methods</p> <p>In...

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Bibliographic Details
Main Authors: Qi Kemin, Deckelbaum Richard J, Shen Wenwen, Liu Xinli, Fan Chaonan
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Nutrition & Metabolism
Subjects:
n-3 polyunsaturated fatty acids
DNA methylation
obesity
leptin
leptin receptor
pro-opiomelanocortin
mouse
Online Access:http://www.nutritionandmetabolism.com/content/8/1/31

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