Roles for wbtC, wbtI, and kdtA Genes in Lipopolysaccharide Biosynthesis, Protein Glycosylation, Virulence, and Immunogenicity in Francisella tularensis Strain SCHU S4

Roles for wbtC, wbtI, and kdtA Genes in Lipopolysaccharide Biosynthesis, Protein Glycosylation, Virulence, and Immunogenicity in Francisella tularensis Strain SCHU S4

Using a strategy of gene deletion mutagenesis, we have examined the roles of genes putatively involved in lipopolysaccharide biosynthesis in the virulent facultative intracellular bacterial pathogen, Francisella tularensis subspecies tularensis, strain SCHU S4 in LPS biosynthesis, protein glycosylat...

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Bibliographic Details
Main Authors: Susan M. Twine, Evguenii Vinogradov, Helena Lindgren, Anders Sjostedt, J. Wayne Conlan
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Pathogens
Subjects:
Francisella tularensis
lipopolysaccharide
glycosylation
virulence
Online Access:http://www.mdpi.com/2076-0817/1/1/12

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