Establishment of canine mammary gland tumor cell lines harboring PI3K/Akt activation as a therapeutic target

Abstract Canine mammary gland tumors (MGT) have a poor prognosis in intact female canines, posing a clinical challenge. This study aimed to establish novel canine mammary cancer cell lines from primary tumors and characterize their cellular and molecular features to find potential therapeutic drugs....

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Main Authors: Seo-Young Park, Yeong-Bin Baek, Chan-Ho Lee, Hyun-Jin Kim, Hwang-Phill Kim, Young-Jun Jeon, Jung Eun Song, Su-Bin Jung, Hyo-Jin Kim, Kyeong-Seo Moon, Sang-Ik Park, Chang-Min Lee, Sung-Hak Kim
格式: 文件
语言:English
出版: BMC 2024-05-01
丛编:BMC Veterinary Research
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在线阅读:https://doi.org/10.1186/s12917-024-04085-w