Profile of The Chikungunya Infection: A Neglected Vector Borne Disease which is Prevalent In The Rajkot District
Background: Chikungunya Virus has been responsible for significant human morbidity probably for several hundred years; yet in spite of its prevalence, the Chikungunya Virus epidemiology and the mechanisms of virulence and pathogenesis are still poorly understood and undetermined. Aims: This study...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
JCDR Research and Publications Private Limited
2013-06-01
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Series: | Journal of Clinical and Diagnostic Research |
Subjects: | |
Online Access: | https://jcdr.net/articles/PDF/3057/9%20-%205307_E(C)_PF1(M)_F(H)_PF1(PUH)_PFA(PUH)_OLF_u.pdf |
Summary: | Background: Chikungunya Virus has been responsible for significant human morbidity probably for several hundred years;
yet in spite of its prevalence, the Chikungunya Virus epidemiology and the mechanisms of virulence and pathogenesis are
still poorly understood and undetermined.
Aims: This study was done to show that the Chikungunya infection has shown a change in its pattern of occurrence with
respect to the clinical features, the gender and the age group
which are predominant and the season of the outbreak. The
present study was conducted to evaluate the features of the
Chikugunya infection in patients with acute febrile illness from
various geographical regions of Rajkot district, Gujarat, India.
Type of Study: A cross-sectional study, multi centric study.
Statistical method: The Chi-square test for the goodness of
the fit and independence.
Methods: One hundred ninty three serum samples of suspected cases of patients who attended the outdoor and indoor
patients departments at a tertiary care hospital, Rajkot and the
primary health centres, the community health centre and the
urban health centres that were covered in the Rajkot district,
which were collected during the period of one year from 1st
January 2011 to 25th December 2011, were studied. The sera
were processed and tested for the detection of the Chikungunya IgM antibody by using a solid phase, capture micro well
ELISA technology.
Results: Out of the total 193 cases, 84 were positive for the
Chikungunya IgM antibody. Out of the total 84 positive cases,
32 were males (38.09%) and 52 were females (61.9%). Female
patients showed more prevalence of this disease. A majority
of the patients presented with fever, headache and joint pain:
44(52.38%). The highest prevalence of Chikungunya was found
in the 40-50 years age group, which occurred in 34 (40.47%)
cases. In the months of November and December, the occurrence of Chikungunya was more.
Conclusion: This study emphasizes the need for a continuous surveillance on the disease burden by using multiple diagnostic tests and it also warrants the need for appropriate
molecular diagnostic techniques for an early detection of the
Chikungunya virus. |
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ISSN: | 2249-782X 0973-709X |