Attenuation of Dopaminergic Neurodegeneration in a <i>C. elegans</i> Parkinson’s Model through Regulation of Xanthine Dehydrogenase (XDH-1) Expression by the RNA Editase, ADR-2

Attenuation of Dopaminergic Neurodegeneration in a <i>C. elegans</i> Parkinson’s Model through Regulation of Xanthine Dehydrogenase (XDH-1) Expression by the RNA Editase, ADR-2

Differential RNA editing by adenosine deaminases that act on RNA (ADARs) has been implicated in several neurological disorders, including Parkinson’s disease (PD). Here, we report results of a RNAi screen of genes differentially regulated in <i>adr-2</i> mutants, normally encoding the on...

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Bibliographic Details
Main Authors: Lindsey A. Starr, Luke E. McKay, Kylie N. Peter, Lena M. Seyfarth, Laura A. Berkowitz, Kim A. Caldwell, Guy A. Caldwell
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Developmental Biology
Subjects:
ABC transporter
α-synuclein
ADAR
<i>C. elegans</i>
dopamine
neurodegeneration
Online Access:https://www.mdpi.com/2221-3759/11/2/20

Internet

https://www.mdpi.com/2221-3759/11/2/20

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