Incidence of bleb-associated endophthalmitis in the United States
Kamyar Vaziri,1 Krishna Kishor,1 Stephen G Schwartz,1 Arindel S Maharaj,1 Darius M Moshfeghi,2 Andrew A Moshfeghi,3 Harry W Flynn Jr1 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USA; 2Department of Ophthalmology, Byers&nb...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2015-02-01
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| Series: | Clinical Ophthalmology |
| Online Access: | http://www.dovepress.com/incidence-of-bleb-associated-endophthalmitis-innbspthe-united-states-peer-reviewed-article-OPTH |
| _version_ | 1818904591103688704 |
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| author | Vaziri K Kishor K Schwartz SG Maharaj AS Moshfeghi DM Moshfeghi AA Flynn HW Jr |
| author_facet | Vaziri K Kishor K Schwartz SG Maharaj AS Moshfeghi DM Moshfeghi AA Flynn HW Jr |
| author_sort | Vaziri K |
| collection | DOAJ |
| description | Kamyar Vaziri,1 Krishna Kishor,1 Stephen G Schwartz,1 Arindel S Maharaj,1 Darius M Moshfeghi,2 Andrew A Moshfeghi,3 Harry W Flynn Jr1 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USA; 2Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA; 3USC Eye Institute, Department of Ophthalmology, University of Southern California Keck School of Medicine, Los Angeles, CA, USA Purpose: To evaluate the 5-year incidence rate of blebitis and bleb-associated endophthalmitis in the United States. Methods: In this retrospective cross-sectional study, we utilized a large commercial health insurance claim-based database during 2007–2011 and identified all patients who had a record of trabeculectomy in 2007. These patients were followed until the end of 2011. During the follow-up period, all incidences of blebitis, confirmed bleb-associated endophthalmitis, and presumed bleb-associated endophthalmitis were recorded. Kaplan–Meier survival analysis was utilized to calculate 5-year cumulative incidence rates of blebitis and bleb-associated endophthalmitis following trabeculectomy procedures. Results: Among the 1,461 trabeculectomies included in our analysis, eight cases of blebitis, five cases of confirmed bleb-associated endophthalmitis, and eight cases of presumed bleb-associated endophthalmitis were identified. We found that the 5-year cumulative incidence of blebitis was 0.55%±0.19%. The 5-year cumulative incidence of bleb-associated endophthalmitis was 0.45%±0.2% when only confirmed cases were included and 1.3%±0.34% when presumed cases were also added to the analysis. The mean time from procedure to diagnosis was 45 months for blebitis and 33 months for bleb-associated endophthalmitis. Conclusion: Blebitis and bleb-related endophthalmitis are uncommon in the United States. The 5-year cumulative incidence was 0.55% for blebitis and 0.45%–1.3% for bleb-associated endophthalmitis. Keywords: bleb, blebitis, bleb-associated endophthalmitis, trabeculectomy |
| first_indexed | 2024-12-19T21:09:52Z |
| format | Article |
| id | doaj.art-be60cce1c0cd49f6998345cba82a0f88 |
| institution | Directory Open Access Journal |
| issn | 1177-5483 |
| language | English |
| last_indexed | 2024-12-19T21:09:52Z |
| publishDate | 2015-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-be60cce1c0cd49f6998345cba82a0f882022-12-21T20:05:31ZengDove Medical PressClinical Ophthalmology1177-54832015-02-012015default31732220428Incidence of bleb-associated endophthalmitis in the United StatesVaziri KKishor KSchwartz SGMaharaj ASMoshfeghi DMMoshfeghi AAFlynn HW JrKamyar Vaziri,1 Krishna Kishor,1 Stephen G Schwartz,1 Arindel S Maharaj,1 Darius M Moshfeghi,2 Andrew A Moshfeghi,3 Harry W Flynn Jr1 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USA; 2Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA; 3USC Eye Institute, Department of Ophthalmology, University of Southern California Keck School of Medicine, Los Angeles, CA, USA Purpose: To evaluate the 5-year incidence rate of blebitis and bleb-associated endophthalmitis in the United States. Methods: In this retrospective cross-sectional study, we utilized a large commercial health insurance claim-based database during 2007–2011 and identified all patients who had a record of trabeculectomy in 2007. These patients were followed until the end of 2011. During the follow-up period, all incidences of blebitis, confirmed bleb-associated endophthalmitis, and presumed bleb-associated endophthalmitis were recorded. Kaplan–Meier survival analysis was utilized to calculate 5-year cumulative incidence rates of blebitis and bleb-associated endophthalmitis following trabeculectomy procedures. Results: Among the 1,461 trabeculectomies included in our analysis, eight cases of blebitis, five cases of confirmed bleb-associated endophthalmitis, and eight cases of presumed bleb-associated endophthalmitis were identified. We found that the 5-year cumulative incidence of blebitis was 0.55%±0.19%. The 5-year cumulative incidence of bleb-associated endophthalmitis was 0.45%±0.2% when only confirmed cases were included and 1.3%±0.34% when presumed cases were also added to the analysis. The mean time from procedure to diagnosis was 45 months for blebitis and 33 months for bleb-associated endophthalmitis. Conclusion: Blebitis and bleb-related endophthalmitis are uncommon in the United States. The 5-year cumulative incidence was 0.55% for blebitis and 0.45%–1.3% for bleb-associated endophthalmitis. Keywords: bleb, blebitis, bleb-associated endophthalmitis, trabeculectomyhttp://www.dovepress.com/incidence-of-bleb-associated-endophthalmitis-innbspthe-united-states-peer-reviewed-article-OPTH |
| spellingShingle | Vaziri K Kishor K Schwartz SG Maharaj AS Moshfeghi DM Moshfeghi AA Flynn HW Jr Incidence of bleb-associated endophthalmitis in the United States Clinical Ophthalmology |
| title | Incidence of bleb-associated endophthalmitis in the United States |
| title_full | Incidence of bleb-associated endophthalmitis in the United States |
| title_fullStr | Incidence of bleb-associated endophthalmitis in the United States |
| title_full_unstemmed | Incidence of bleb-associated endophthalmitis in the United States |
| title_short | Incidence of bleb-associated endophthalmitis in the United States |
| title_sort | incidence of bleb associated endophthalmitis in nbsp the united states |
| url | http://www.dovepress.com/incidence-of-bleb-associated-endophthalmitis-innbspthe-united-states-peer-reviewed-article-OPTH |
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