Choroidal Melanocytic Hamartoma
We report on a case series that revealed flat, choroidal lesions on optical coherence tomography (OCT) and on enface MultiColor<sup>®</sup> (MCI) imaging of the fundus but were not noticeable on clinical examination or conventional color fundus images. This observational study included 1...
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| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/20/5983 |
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| author | Ramesh Venkatesh Sameeksha Agrawal Nikitha Gurram Reddy Rubble Mangla Naresh Kumar Yadav Jay Chhablani |
| author_facet | Ramesh Venkatesh Sameeksha Agrawal Nikitha Gurram Reddy Rubble Mangla Naresh Kumar Yadav Jay Chhablani |
| author_sort | Ramesh Venkatesh |
| collection | DOAJ |
| description | We report on a case series that revealed flat, choroidal lesions on optical coherence tomography (OCT) and on enface MultiColor<sup>®</sup> (MCI) imaging of the fundus but were not noticeable on clinical examination or conventional color fundus images. This observational study included 12 eyes from 11 patients who had distinct, orange-colored lesions on MCI. Retinal imaging was conducted using conventional color fundus photography and OCT. On the color fundus images and the blue and green reflectance channels of MCI, each of the lesions was difficult to distinguish. On the infrared channel, the lesion was identified as bright white in color and bright orange on the multicolor image. The lesion was identified on OCT as a flat, homogeneous hyperreflective lesion involving the choroid, with an intact overlying retinal pigment epithelium and retinal layers. A comparison of the clinical and imaging features with other known entities led to the conclusion that the lesion was a distinct clinical entity. The presence of melanin in the lesion was confirmed based on the retinal imaging findings and the light absorption properties of melanin. As a result, the lesion was named as ‘choroidal melanocytic hamartoma’. A longer follow-up is required to confirm the benign nature of this clinical entity. |
| first_indexed | 2024-03-09T20:03:12Z |
| format | Article |
| id | doaj.art-be6296e6e1f7499f91ab3a20132aaaf6 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T20:03:12Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-be6296e6e1f7499f91ab3a20132aaaf62023-11-24T00:39:07ZengMDPI AGJournal of Clinical Medicine2077-03832022-10-011120598310.3390/jcm11205983Choroidal Melanocytic HamartomaRamesh Venkatesh0Sameeksha Agrawal1Nikitha Gurram Reddy2Rubble Mangla3Naresh Kumar Yadav4Jay Chhablani5Narayana Nethralaya, Department of Retina and Vitreous, #121/C, Chord Road, 1st R Block Rajaji Nagar, Bangalore 560010, IndiaNarayana Nethralaya, Department of Retina and Vitreous, #121/C, Chord Road, 1st R Block Rajaji Nagar, Bangalore 560010, IndiaNarayana Nethralaya, Department of Retina and Vitreous, #121/C, Chord Road, 1st R Block Rajaji Nagar, Bangalore 560010, IndiaNarayana Nethralaya, Department of Retina and Vitreous, #121/C, Chord Road, 1st R Block Rajaji Nagar, Bangalore 560010, IndiaNarayana Nethralaya, Department of Retina and Vitreous, #121/C, Chord Road, 1st R Block Rajaji Nagar, Bangalore 560010, IndiaMedical Retina and Vitreoretinal Surgery, University of Pittsburgh School of Medicine, 203 Lothrop Street, Suite 800, Pittsburg, PA 15213, USAWe report on a case series that revealed flat, choroidal lesions on optical coherence tomography (OCT) and on enface MultiColor<sup>®</sup> (MCI) imaging of the fundus but were not noticeable on clinical examination or conventional color fundus images. This observational study included 12 eyes from 11 patients who had distinct, orange-colored lesions on MCI. Retinal imaging was conducted using conventional color fundus photography and OCT. On the color fundus images and the blue and green reflectance channels of MCI, each of the lesions was difficult to distinguish. On the infrared channel, the lesion was identified as bright white in color and bright orange on the multicolor image. The lesion was identified on OCT as a flat, homogeneous hyperreflective lesion involving the choroid, with an intact overlying retinal pigment epithelium and retinal layers. A comparison of the clinical and imaging features with other known entities led to the conclusion that the lesion was a distinct clinical entity. The presence of melanin in the lesion was confirmed based on the retinal imaging findings and the light absorption properties of melanin. As a result, the lesion was named as ‘choroidal melanocytic hamartoma’. A longer follow-up is required to confirm the benign nature of this clinical entity.https://www.mdpi.com/2077-0383/11/20/5983choroidmelaninhamartomamultimodal imaging |
| spellingShingle | Ramesh Venkatesh Sameeksha Agrawal Nikitha Gurram Reddy Rubble Mangla Naresh Kumar Yadav Jay Chhablani Choroidal Melanocytic Hamartoma Journal of Clinical Medicine choroid melanin hamartoma multimodal imaging |
| title | Choroidal Melanocytic Hamartoma |
| title_full | Choroidal Melanocytic Hamartoma |
| title_fullStr | Choroidal Melanocytic Hamartoma |
| title_full_unstemmed | Choroidal Melanocytic Hamartoma |
| title_short | Choroidal Melanocytic Hamartoma |
| title_sort | choroidal melanocytic hamartoma |
| topic | choroid melanin hamartoma multimodal imaging |
| url | https://www.mdpi.com/2077-0383/11/20/5983 |
| work_keys_str_mv | AT rameshvenkatesh choroidalmelanocytichamartoma AT sameekshaagrawal choroidalmelanocytichamartoma AT nikithagurramreddy choroidalmelanocytichamartoma AT rubblemangla choroidalmelanocytichamartoma AT nareshkumaryadav choroidalmelanocytichamartoma AT jaychhablani choroidalmelanocytichamartoma |