Cultivation of Head and Neck Squamous Cell Carcinoma Cells with Wound Fluid Leads to Cisplatin Resistance via Epithelial-Mesenchymal Transition Induction

Cultivation of Head and Neck Squamous Cell Carcinoma Cells with Wound Fluid Leads to Cisplatin Resistance via Epithelial-Mesenchymal Transition Induction

Locoregional recurrence is a major reason for therapy failure after surgical resection of head and neck squamous cell carcinoma (HNSCC). The physiological process of postoperative wound healing could potentially support the proliferation of remaining tumor cells. The aim of this study was to evaluat...

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Bibliographic Details
Main Authors: Till Jasper Meyer, Manuel Stöth, Helena Moratin, Pascal Ickrath, Marietta Herrmann, Norbert Kleinsasser, Rudolf Hagen, Stephan Hackenberg, Agmal Scherzad
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
cell proliferation
wound fluid
epithelial-mesenchymal transition
cisplatin resistance
Interleukin
head and neck squamous cell carcinoma
Online Access:https://www.mdpi.com/1422-0067/22/9/4474

Internet

https://www.mdpi.com/1422-0067/22/9/4474

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