Colonization and virulence factors of methicillin resistant Staphylococcus aureus in a pediatric population in Montería, Colombia
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is able to colonize the human body, most frequently the nostrils, but also the hands, perineum and throat. Such colonization has been proposed as a risk factor to acquire future infections. Objective: To determine the prevalence, and t...
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| Format: | Article |
| Language: | Spanish |
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Universidad de Antioquia
2015-07-01
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| Series: | Iatreia |
| Subjects: | |
| Online Access: | http://aprendeenlinea.udea.edu.co/revistas/index.php/iatreia/article/view/20019 |
| _version_ | 1818808267474731008 |
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| author | Ricardo-Caldera, Dina Marcela Buelvas-Doria, Francisco Alberto Escobar-Pérez, Javier Antonio Tovar-Acero, Catalina |
| author_facet | Ricardo-Caldera, Dina Marcela Buelvas-Doria, Francisco Alberto Escobar-Pérez, Javier Antonio Tovar-Acero, Catalina |
| author_sort | Ricardo-Caldera, Dina Marcela |
| collection | DOAJ |
| description | Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is able to colonize the human body, most frequently the nostrils, but also the hands, perineum and throat. Such colonization has been proposed as a risk factor to acquire future infections. Objective: To determine the prevalence, and the microbiological
and molecular characteristics of MRSA in healthy children. Methodology: A cross-sectional descriptive study was done of 150 children from 13 day care centers in Montería, Colombia. Nasal and throat swabs were obtained. The isolates were identified and characterized by microbiological and molecular methods. Results: The MRSA colonization rate was 9.3% (14/150). 62.5% of the isolates carried the subtype IVc of SCCmec, and 87.5% had the genes encoding for PVL and Sek, while 81.2% carried the gene bsaB. Conclusion: The percentage of colonization found is one of the highest reported among children from the Colombian Caribbean region, and the isolates have virulence factors that have been associated with an aggressive clinical course. |
| first_indexed | 2024-12-18T19:38:51Z |
| format | Article |
| id | doaj.art-be661e6f9dba48408c158b9f98d37b49 |
| institution | Directory Open Access Journal |
| issn | 0121-0793 2011-7965 |
| language | Spanish |
| last_indexed | 2024-12-18T19:38:51Z |
| publishDate | 2015-07-01 |
| publisher | Universidad de Antioquia |
| record_format | Article |
| series | Iatreia |
| spelling | doaj.art-be661e6f9dba48408c158b9f98d37b492022-12-21T20:55:30ZspaUniversidad de AntioquiaIatreia0121-07932011-79652015-07-0128325926810.17533/udea.iatreia.v28n3a04Colonization and virulence factors of methicillin resistant Staphylococcus aureus in a pediatric population in Montería, ColombiaRicardo-Caldera, Dina Marcela0Buelvas-Doria, Francisco Alberto1Escobar-Pérez, Javier Antonio2Tovar-Acero, Catalina3Universidad del Sinú, Montería, ColombiaUniversidad del Sinú, Montería, ColombiaUniversidad El Bosque, Bogotá, ColombiaUniversidad del Sinú, Montería, ColombiaIntroduction: Methicillin-resistant Staphylococcus aureus (MRSA) is able to colonize the human body, most frequently the nostrils, but also the hands, perineum and throat. Such colonization has been proposed as a risk factor to acquire future infections. Objective: To determine the prevalence, and the microbiological and molecular characteristics of MRSA in healthy children. Methodology: A cross-sectional descriptive study was done of 150 children from 13 day care centers in Montería, Colombia. Nasal and throat swabs were obtained. The isolates were identified and characterized by microbiological and molecular methods. Results: The MRSA colonization rate was 9.3% (14/150). 62.5% of the isolates carried the subtype IVc of SCCmec, and 87.5% had the genes encoding for PVL and Sek, while 81.2% carried the gene bsaB. Conclusion: The percentage of colonization found is one of the highest reported among children from the Colombian Caribbean region, and the isolates have virulence factors that have been associated with an aggressive clinical course.http://aprendeenlinea.udea.edu.co/revistas/index.php/iatreia/article/view/20019ChildChild Day Care CentersMethicillin resistant Staphylococcus aureusVirulence Factors |
| spellingShingle | Ricardo-Caldera, Dina Marcela Buelvas-Doria, Francisco Alberto Escobar-Pérez, Javier Antonio Tovar-Acero, Catalina Colonization and virulence factors of methicillin resistant Staphylococcus aureus in a pediatric population in Montería, Colombia Iatreia Child Child Day Care Centers Methicillin resistant Staphylococcus aureus Virulence Factors |
| title | Colonization and virulence factors of methicillin resistant Staphylococcus aureus in a pediatric population in Montería, Colombia |
| title_full | Colonization and virulence factors of methicillin resistant Staphylococcus aureus in a pediatric population in Montería, Colombia |
| title_fullStr | Colonization and virulence factors of methicillin resistant Staphylococcus aureus in a pediatric population in Montería, Colombia |
| title_full_unstemmed | Colonization and virulence factors of methicillin resistant Staphylococcus aureus in a pediatric population in Montería, Colombia |
| title_short | Colonization and virulence factors of methicillin resistant Staphylococcus aureus in a pediatric population in Montería, Colombia |
| title_sort | colonization and virulence factors of methicillin resistant staphylococcus aureus in a pediatric population in monteria colombia |
| topic | Child Child Day Care Centers Methicillin resistant Staphylococcus aureus Virulence Factors |
| url | http://aprendeenlinea.udea.edu.co/revistas/index.php/iatreia/article/view/20019 |
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