Electrodermal activity and heart rate variability for detection of peripheral abnormalities in type 2 diabetes: A review
Modern medicine exhibits an upward trend towards non-invasive methods for early detection of disease and long-term monitoring of patients’ health. Diabetes mellitus and its complications are a promising area for implementation of new medical diagnostic devices. One of the most serious complications...
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Format: | Article |
Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2023-09-01
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Series: | Biomolecules & Biomedicine |
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Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/8561 |
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author | Matej Žnidarič Dominik Škrinjar Alen Kapel |
author_facet | Matej Žnidarič Dominik Škrinjar Alen Kapel |
author_sort | Matej Žnidarič |
collection | DOAJ |
description | Modern medicine exhibits an upward trend towards non-invasive methods for early detection of disease and long-term monitoring of patients’ health. Diabetes mellitus and its complications are a promising area for implementation of new medical diagnostic devices. One of the most serious complications of diabetes is diabetic foot ulcer. The main causes responsible for diabetic foot ulcer are ischemia caused by peripheral artery disease and diabetic neuropathy caused by polyol pathway-induced oxidative stress. Autonomic neuropathy impairs function of sweat glands, which can be measured by electrodermal activity. On the other hand, autonomic neuropathy leads to changes in heart rate variability, which is used to assess autonomic regulation of the sinoatrial node. Both methods are enough sensitive to detect pathological changes caused by autonomic neuropathy and are promising screening methods for early diagnosis of diabetic neuropathy, which could prevent the onset of diabetic ulcer.
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first_indexed | 2024-04-24T23:40:27Z |
format | Article |
id | doaj.art-be699f53d1dd4cacb2e4ce478ded0af8 |
institution | Directory Open Access Journal |
issn | 2831-0896 2831-090X |
language | English |
last_indexed | 2024-04-24T23:40:27Z |
publishDate | 2023-09-01 |
publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
record_format | Article |
series | Biomolecules & Biomedicine |
spelling | doaj.art-be699f53d1dd4cacb2e4ce478ded0af82024-03-15T13:22:34ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2023-09-0123510.17305/bb.2022.8561Electrodermal activity and heart rate variability for detection of peripheral abnormalities in type 2 diabetes: A reviewMatej Žnidarič0https://orcid.org/0000-0001-5015-9085Dominik Škrinjar1https://orcid.org/0000-0002-1354-7705Alen Kapel2https://orcid.org/0000-0002-1522-9866Faculty of Medicine, University of Maribor, Maribor, Slovenia Faculty of Medicine, University of Maribor, Maribor, Slovenia Faculty of Health and Social Sciences, Slovenj Gradec, Slovenia; Alma Mater Europaea, Maribor, Slovenia; Modus Medical, Maribor, SloveniaModern medicine exhibits an upward trend towards non-invasive methods for early detection of disease and long-term monitoring of patients’ health. Diabetes mellitus and its complications are a promising area for implementation of new medical diagnostic devices. One of the most serious complications of diabetes is diabetic foot ulcer. The main causes responsible for diabetic foot ulcer are ischemia caused by peripheral artery disease and diabetic neuropathy caused by polyol pathway-induced oxidative stress. Autonomic neuropathy impairs function of sweat glands, which can be measured by electrodermal activity. On the other hand, autonomic neuropathy leads to changes in heart rate variability, which is used to assess autonomic regulation of the sinoatrial node. Both methods are enough sensitive to detect pathological changes caused by autonomic neuropathy and are promising screening methods for early diagnosis of diabetic neuropathy, which could prevent the onset of diabetic ulcer. https://www.bjbms.org/ojs/index.php/bjbms/article/view/8561Diabetes mellitusdiabetic foot ulcerautonomic neuropathyelectrodermal activityheart rate variability |
spellingShingle | Matej Žnidarič Dominik Škrinjar Alen Kapel Electrodermal activity and heart rate variability for detection of peripheral abnormalities in type 2 diabetes: A review Biomolecules & Biomedicine Diabetes mellitus diabetic foot ulcer autonomic neuropathy electrodermal activity heart rate variability |
title | Electrodermal activity and heart rate variability for detection of peripheral abnormalities in type 2 diabetes: A review |
title_full | Electrodermal activity and heart rate variability for detection of peripheral abnormalities in type 2 diabetes: A review |
title_fullStr | Electrodermal activity and heart rate variability for detection of peripheral abnormalities in type 2 diabetes: A review |
title_full_unstemmed | Electrodermal activity and heart rate variability for detection of peripheral abnormalities in type 2 diabetes: A review |
title_short | Electrodermal activity and heart rate variability for detection of peripheral abnormalities in type 2 diabetes: A review |
title_sort | electrodermal activity and heart rate variability for detection of peripheral abnormalities in type 2 diabetes a review |
topic | Diabetes mellitus diabetic foot ulcer autonomic neuropathy electrodermal activity heart rate variability |
url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/8561 |
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