Evaluation of the cell-free DNA integrity index as a liquid biopsy marker to differentiate hepatocellular carcinoma from chronic liver disease

Evaluation of the cell-free DNA integrity index as a liquid biopsy marker to differentiate hepatocellular carcinoma from chronic liver disease

Background: Hepatocellular carcinoma (HCC) occurs in the majority of patients with underlying chronic liver disease (CLD) of viral and non-viral etiologies, which requires screening for early HCC diagnosis. Liquid biopsy holds great promise now for early detection, prognosis, and assessment of respo...

Full description

Bibliographic Details
Main Authors: Sonu Kumar, Neeti Nadda, Shashi Paul, Shivanand Gamanagatti, Nihar Ranjan Dash, Perumal Vanamail, Anoop Saraya, Shalimar, Baibaswata Nayak
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Molecular Biosciences
Subjects:
liquid biopsy
circulating free DNA
circulating tumor DNA
hepatocellular carcinoma
chronic liver disease
DNA integrity index
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.1024193/full

Similar Items

Similar Items