Transcriptomic and lipid profiling analysis reveals a functional interplay between testosterone and growth hormone in hypothyroid liver

Transcriptomic and lipid profiling analysis reveals a functional interplay between testosterone and growth hormone in hypothyroid liver

Preclinical and clinical studies suggest that hypothyroidism might cause hepatic endocrine and metabolic disturbances with features that mimic deficiencies of testosterone and/or GH. The absence of physiological interactions between testosterone and GH can be linked to male differentiated liver dise...

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Bibliographic Details
Main Authors: Leandro Fernández-Pérez, Borja Guerra, Carlota Recio, Juan José Cabrera-Galván, Irma García, Juan Vladimir De La Rosa, Antonio Castrillo, Diego Iglesias-Gato, Mario Díaz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Endocrinology
Subjects:
hypothyroidism
testosterone
GH
liver
transcriptome
lipids
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1266150/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1266150/full

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