Subcutaneous Epithelioid Sarcoma Originating from Multiple Metastases of Uterine Leiomyosarcoma
Objective: We present a rare case of loin subcutaneous epithelioid sarcoma originating from the multiple metastases of a uterine leiomyosarcoma. Case Report: A 54-year-old postmenopausal woman, gravida 6, para 6, presented to the general surgery outpatient department (OPD). Loin mass excisional surg...
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| Format: | Article |
| Language: | English |
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Elsevier
2005-06-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S102845590960139X |
| _version_ | 1818944177546723328 |
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| author | Jen-Ruei Chen Kung-Liahng Wang Kuo-Ming Chang Tao-Yeuan Wang |
| author_facet | Jen-Ruei Chen Kung-Liahng Wang Kuo-Ming Chang Tao-Yeuan Wang |
| author_sort | Jen-Ruei Chen |
| collection | DOAJ |
| description | Objective: We present a rare case of loin subcutaneous epithelioid sarcoma originating from the multiple metastases of a uterine leiomyosarcoma.
Case Report: A 54-year-old postmenopausal woman, gravida 6, para 6, presented to the general surgery outpatient department (OPD). Loin mass excisional surgery was performed on August 6, 2002, and she was diagnosed with epithelioid sarcoma. Sharp intermittent lower abdominal pain, low grade fever and back pain were noted on the fifth day after this surgery. She was transferred to the gynecology OPD. Laparotomy, on August 26, 2002, found an enlarged uterus with multiple nodules on the liver surface, mesentery, small intestine surface, omentum and sub-diaphragm. Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed because uterine fibroid was the most suspicious originating site of these metastatic lesions. After laparotomy, the abdominal distension and pain continued with little improvement. She died on September 17, 2002, as a result of multiple metastases of leiomyosarcoma in both lung fields and respiratory failure.
Conclusion: The abrupt appearance of skin or subcutaneous nodules should prompt the clinician to consider the possibility of metastatic disease, even in patients with no known history of malignant neoplasms. Uterine leiomyosarcomas are rarely diagnosed preoperatively, and the prognosis of uterine sarcoma is notorious for its difficult determination. The frequent development of distant metastases is the main reason for the poor survival observed in uterine sarcoma compared with other uterine malignancies. |
| first_indexed | 2024-12-20T07:39:05Z |
| format | Article |
| id | doaj.art-be787c8913514e87a18a6c364d010aeb |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-12-20T07:39:05Z |
| publishDate | 2005-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-be787c8913514e87a18a6c364d010aeb2022-12-21T19:48:11ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592005-06-0144219219510.1016/S1028-4559(09)60139-XSubcutaneous Epithelioid Sarcoma Originating from Multiple Metastases of Uterine LeiomyosarcomaJen-Ruei Chen0Kung-Liahng Wang1Kuo-Ming Chang2Tao-Yeuan Wang3Department of Obstetrics and Gynecology, Taipei, TaiwanDepartment of Obstetrics and Gynecology, Taipei, TaiwanDepartment of Pathology, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pathology, Mackay Memorial Hospital, Taipei, TaiwanObjective: We present a rare case of loin subcutaneous epithelioid sarcoma originating from the multiple metastases of a uterine leiomyosarcoma. Case Report: A 54-year-old postmenopausal woman, gravida 6, para 6, presented to the general surgery outpatient department (OPD). Loin mass excisional surgery was performed on August 6, 2002, and she was diagnosed with epithelioid sarcoma. Sharp intermittent lower abdominal pain, low grade fever and back pain were noted on the fifth day after this surgery. She was transferred to the gynecology OPD. Laparotomy, on August 26, 2002, found an enlarged uterus with multiple nodules on the liver surface, mesentery, small intestine surface, omentum and sub-diaphragm. Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed because uterine fibroid was the most suspicious originating site of these metastatic lesions. After laparotomy, the abdominal distension and pain continued with little improvement. She died on September 17, 2002, as a result of multiple metastases of leiomyosarcoma in both lung fields and respiratory failure. Conclusion: The abrupt appearance of skin or subcutaneous nodules should prompt the clinician to consider the possibility of metastatic disease, even in patients with no known history of malignant neoplasms. Uterine leiomyosarcomas are rarely diagnosed preoperatively, and the prognosis of uterine sarcoma is notorious for its difficult determination. The frequent development of distant metastases is the main reason for the poor survival observed in uterine sarcoma compared with other uterine malignancies.http://www.sciencedirect.com/science/article/pii/S102845590960139Xskin metastasessubcutaneous noduleuterine leiomyosarcoma |
| spellingShingle | Jen-Ruei Chen Kung-Liahng Wang Kuo-Ming Chang Tao-Yeuan Wang Subcutaneous Epithelioid Sarcoma Originating from Multiple Metastases of Uterine Leiomyosarcoma Taiwanese Journal of Obstetrics & Gynecology skin metastases subcutaneous nodule uterine leiomyosarcoma |
| title | Subcutaneous Epithelioid Sarcoma Originating from Multiple Metastases of Uterine Leiomyosarcoma |
| title_full | Subcutaneous Epithelioid Sarcoma Originating from Multiple Metastases of Uterine Leiomyosarcoma |
| title_fullStr | Subcutaneous Epithelioid Sarcoma Originating from Multiple Metastases of Uterine Leiomyosarcoma |
| title_full_unstemmed | Subcutaneous Epithelioid Sarcoma Originating from Multiple Metastases of Uterine Leiomyosarcoma |
| title_short | Subcutaneous Epithelioid Sarcoma Originating from Multiple Metastases of Uterine Leiomyosarcoma |
| title_sort | subcutaneous epithelioid sarcoma originating from multiple metastases of uterine leiomyosarcoma |
| topic | skin metastases subcutaneous nodule uterine leiomyosarcoma |
| url | http://www.sciencedirect.com/science/article/pii/S102845590960139X |
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