Downregulated miR-181a alleviates H2O2-induced oxidative stress and cellular senescence by targeting PDIA6 in human foreskin fibroblasts

Abstract Background Oxidative stress is strongly associated with cellular senescence. Numerous studies have indicated that microRNAs (miRNAs) play a critical part in cellular senescence. MiR-181a was reported to induce cellular senescence, however, the potential mechanism of miR-181a in hydrogen pe...

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Bibliographic Details
Main Authors: Yan Huang, Huimin Yan, Yanqing Yang, Jinfei Zhou, Qijun Xu, Hu Meng
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia 2023-04-01
Series:Anais Brasileiros de Dermatologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962023000100017&lng=en&tlng=en