INTRALESIONAL BLEOMYCIN IN TREATMENT OF PLANTAR WARTS
Objective: To assess the efficacy of intralesional bleomycin in treating plantar warts. Study Design: Descriptive cross-sectional study. Place and Duration of Study: Combined Military Hospital Lahore, from Jan 2015 to Sep 2015. Material and Methods: The study was conducted in Dermatol...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Army Medical College Rawalpindi
2019-02-01
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| Series: | Pakistan Armed Forces Medical Journal |
| Subjects: | |
| Online Access: | https://www.pafmj.org/index.php/PAFMJ/article/view/2522/2077 |
| _version_ | 1819007170811789312 |
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| author | Ayesha Khokhar Salman Arif Farrukh Hussain |
| author_facet | Ayesha Khokhar Salman Arif Farrukh Hussain |
| author_sort | Ayesha Khokhar |
| collection | DOAJ |
| description | Objective:
To assess the efficacy of intralesional bleomycin in treating plantar warts.
Study Design: Descriptive cross-sectional study.
Place and Duration of Study: Combined Military Hospital Lahore, from Jan 2015 to Sep 2015.
Material and Methods:
The study was conducted in Dermatology outpatient department, Combined Military Hospital Lahore, from Jan 2015 to Sep 2015. Total of 60 plantar warts in 20 patients were treated with 1 mg/ml intralesional injection of bleomycin. Patients received a total of four doses of bleomycin every three weeks, and were followed for next three months. We categorized the response to treatment as complete or partial resolution, and nonresponsive.
Results:
Out of 60 warts 46 warts (76.66%) showed complete resolution and 8 (13.33%) warts showed partial resolution (p<0.001). The cure rate was better in warts smaller than 20 mm in diameter in comparison with larger lesions. After six months follow-up, 3 (15%) of the completely resolved warts showed recurrence. Recurrence was more among those with greater number of warts.
Conclusion:
Intralesional bleomycin injections were found to be a reliable, safe and acceptable mode of treatment for plantar warts. |
| first_indexed | 2024-12-21T00:20:20Z |
| format | Article |
| id | doaj.art-be85bf3f218e46e7964b5f7b6fcaa265 |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-12-21T00:20:20Z |
| publishDate | 2019-02-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-be85bf3f218e46e7964b5f7b6fcaa2652022-12-21T19:22:06ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422019-02-01691200204INTRALESIONAL BLEOMYCIN IN TREATMENT OF PLANTAR WARTSAyesha Khokhar0Salman Arif1Farrukh Hussain2Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanCombined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanCombined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanObjective: To assess the efficacy of intralesional bleomycin in treating plantar warts. Study Design: Descriptive cross-sectional study. Place and Duration of Study: Combined Military Hospital Lahore, from Jan 2015 to Sep 2015. Material and Methods: The study was conducted in Dermatology outpatient department, Combined Military Hospital Lahore, from Jan 2015 to Sep 2015. Total of 60 plantar warts in 20 patients were treated with 1 mg/ml intralesional injection of bleomycin. Patients received a total of four doses of bleomycin every three weeks, and were followed for next three months. We categorized the response to treatment as complete or partial resolution, and nonresponsive. Results: Out of 60 warts 46 warts (76.66%) showed complete resolution and 8 (13.33%) warts showed partial resolution (p<0.001). The cure rate was better in warts smaller than 20 mm in diameter in comparison with larger lesions. After six months follow-up, 3 (15%) of the completely resolved warts showed recurrence. Recurrence was more among those with greater number of warts. Conclusion: Intralesional bleomycin injections were found to be a reliable, safe and acceptable mode of treatment for plantar warts.https://www.pafmj.org/index.php/PAFMJ/article/view/2522/2077plantar wartsintralesional |
| spellingShingle | Ayesha Khokhar Salman Arif Farrukh Hussain INTRALESIONAL BLEOMYCIN IN TREATMENT OF PLANTAR WARTS Pakistan Armed Forces Medical Journal plantar warts intralesional |
| title | INTRALESIONAL BLEOMYCIN IN TREATMENT OF PLANTAR WARTS |
| title_full | INTRALESIONAL BLEOMYCIN IN TREATMENT OF PLANTAR WARTS |
| title_fullStr | INTRALESIONAL BLEOMYCIN IN TREATMENT OF PLANTAR WARTS |
| title_full_unstemmed | INTRALESIONAL BLEOMYCIN IN TREATMENT OF PLANTAR WARTS |
| title_short | INTRALESIONAL BLEOMYCIN IN TREATMENT OF PLANTAR WARTS |
| title_sort | intralesional bleomycin in treatment of plantar warts |
| topic | plantar warts intralesional |
| url | https://www.pafmj.org/index.php/PAFMJ/article/view/2522/2077 |
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