Next generation immuno-oncology tumor profiling using a rapid, non-invasive, computational biophysics biomarker in early-stage breast cancer

Next generation immuno-oncology tumor profiling using a rapid, non-invasive, computational biophysics biomarker in early-stage breast cancer

BackgroundImmuno-oncology (IO) therapies targeting the PD-1/PD-L1 axis, such as immune checkpoint inhibitor (ICI) antibodies, have emerged as promising treatments for early-stage breast cancer (ESBC). Despite immunotherapy's clinical significance, the number of benefiting patients remains small...

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Bibliographic Details
Main Authors: Daniel Cook, Matthew Biancalana, Nicole Liadis, Dorys Lopez Ramos, Yuhan Zhang, Snehal Patel, Joseph R. Peterson, John R. Pfeiffer, John A. Cole, Anuja K. Antony
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Artificial Intelligence
Subjects:
computational biomarker
ESBC
ICI
immuno-oncology
biophysical simulation
virtual tumors
Online Access:https://www.frontiersin.org/articles/10.3389/frai.2023.1153083/full

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