Quercetin Alleviates Pulmonary Fibrosis in Silicotic Mice by Inhibiting Macrophage Transition and TGF-β-Smad2/3 Pathway

Quercetin Alleviates Pulmonary Fibrosis in Silicotic Mice by Inhibiting Macrophage Transition and TGF-β-Smad2/3 Pathway

Silicosis is a pulmonary disease caused by the inhalation of silica. There is a lack of early and effective prevention, diagnosis, and treatment methods, and addressing silicotic fibrosis is crucial. Quercetin, a flavonoid with anti-carcinogenic, anti-inflammatory, and antiviral properties, is known...

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Bibliographic Details
Main Authors: Fei Geng, Lan Zhao, Yuhao Cai, Ying Zhao, Fuyu Jin, Yaqian Li, Tian Li, Xinyu Yang, Shifeng Li, Xuemin Gao, Wenchen Cai, Na Mao, Ying Sun, Hong Xu, Zhongqiu Wei, Fang Yang
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Current Issues in Molecular Biology
Subjects:
quercetin
macrophage-to-myofibroblast transition
silicosis
Online Access:https://www.mdpi.com/1467-3045/45/4/202

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