A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis

Metronidazole is a very widely used drug for the treatment of multiple ailments caused by anaerobic bacteria as well as some protozoan parasites. Though its usual side effects are not very serious, yet sometimes it may cause profound adverse effects like neurotoxicity. We present here a case of li...

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Main Authors: Shruti Chandak, Arjit Agarwal, Arvind Shukla, Pawan Joon
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-01-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/7031/14900_CE[Ra]_F(P)_PF1(VIAK)_PFA(AK)_PF2(PAG).pdf
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author Shruti Chandak
Arjit Agarwal
Arvind Shukla
Pawan Joon
author_facet Shruti Chandak
Arjit Agarwal
Arvind Shukla
Pawan Joon
author_sort Shruti Chandak
collection DOAJ
description Metronidazole is a very widely used drug for the treatment of multiple ailments caused by anaerobic bacteria as well as some protozoan parasites. Though its usual side effects are not very serious, yet sometimes it may cause profound adverse effects like neurotoxicity. We present here a case of liver abscess. The patient was treated for a long time with metronidazole and developed sudden onset neurotoxicity which was diagnosed by MRI. The present case also highlights the need of vigilant monitoring of patients on metronidazole for symptoms of neurotoxicity and the usefulness of MRI for diagnosis of the same.
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spelling doaj.art-be894bbadfa84c0db020128d8dfb81442022-12-22T01:11:35ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-01-01101TD06TD0710.7860/JCDR/2016/14900.7031A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its DiagnosisShruti Chandak0Arjit Agarwal1Arvind Shukla2Pawan Joon3Associate Professor, Department of Radiodiagnosis, Teerthanker Mahaveer Medical College, Moradabad, Uttar Pradesh, India.Assistant Professor, Department of Radiodiagnosis, Teerthanker Mahaveer Medical College, Moradabad, Uttar Pradesh, India.Professor, Department of Radiodiagnosis, Teerthanker Mahaveer Medical College, Moradabad, Uttar Pradesh, India.Junior Resident, Department of Radiodiagnosis, Teerthanker Mahaveer Medical College, Moradabad, Uttar Pradesh, India.Metronidazole is a very widely used drug for the treatment of multiple ailments caused by anaerobic bacteria as well as some protozoan parasites. Though its usual side effects are not very serious, yet sometimes it may cause profound adverse effects like neurotoxicity. We present here a case of liver abscess. The patient was treated for a long time with metronidazole and developed sudden onset neurotoxicity which was diagnosed by MRI. The present case also highlights the need of vigilant monitoring of patients on metronidazole for symptoms of neurotoxicity and the usefulness of MRI for diagnosis of the same.https://jcdr.net/articles/PDF/7031/14900_CE[Ra]_F(P)_PF1(VIAK)_PFA(AK)_PF2(PAG).pdfdentate nucleusliver abscessmetronidazole toxicitymri brain
spellingShingle Shruti Chandak
Arjit Agarwal
Arvind Shukla
Pawan Joon
A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis
Journal of Clinical and Diagnostic Research
dentate nucleus
liver abscess
metronidazole toxicity
mri brain
title A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis
title_full A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis
title_fullStr A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis
title_full_unstemmed A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis
title_short A Case Report of Metronidazole Induced Neurotoxicity in Liver Abscess Patient and the Usefulness of MRI for its Diagnosis
title_sort case report of metronidazole induced neurotoxicity in liver abscess patient and the usefulness of mri for its diagnosis
topic dentate nucleus
liver abscess
metronidazole toxicity
mri brain
url https://jcdr.net/articles/PDF/7031/14900_CE[Ra]_F(P)_PF1(VIAK)_PFA(AK)_PF2(PAG).pdf
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