A descriptive study of the single-nucleotide polymorphisms known to affect the Tacrolimus trough concentration per dose, among a population of kidney failure patients in a tertiary hospital in Ghana

A descriptive study of the single-nucleotide polymorphisms known to affect the Tacrolimus trough concentration per dose, among a population of kidney failure patients in a tertiary hospital in Ghana

Abstract Background The burden of chronic kidney disease (CKD) and kidney failure in Ghana is on the ascendency, with the prevalence of CKD estimated at 13.3%. Patients with CKD who progress to kidney failure require life sustaining kidney replacement therapy (KRT) which is almost exclusively availa...

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Bibliographic Details
Main Authors: Edward Kwakyi, Edmund Tetteh Nartey, Michael Kobina Otabil, Isaac Asiedu-Gyekye, Samuel Yao Ahorhorlu, Vincent Bioma, William Kudzi
Format: Article
Language:English
Published: BMC 2024-07-01
Series:BMC Research Notes
Subjects:
Tacrolimus
Single-nucleotide polymorphisms
Korle-bu Teaching Hospital
CYP3A4
CYP3A5
MDR1
Online Access:https://doi.org/10.1186/s13104-024-06868-8

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