Synthesis, Computational Pharmacokinetics Report, Conceptual DFT-Based Calculations and Anti-Acetylcholinesterase Activity of Hydroxyapatite Nanoparticles Derived From Acorus Calamus Plant Extract

Synthesis, Computational Pharmacokinetics Report, Conceptual DFT-Based Calculations and Anti-Acetylcholinesterase Activity of Hydroxyapatite Nanoparticles Derived From Acorus Calamus Plant Extract

Over the years, Alzheimer’s disease (AD) treatments have been a major focus, culminating in the identification of promising therapeutic targets. A herbal therapy approach has been required by the demand of AD stage-dependent optimal settings. Present study describes the evaluation of anti-acetylchol...

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Main Authors: Sushma Pradeep, Anisha S. Jain, Chandan Dharmashekara, Shashanka K. Prasad, Nagaraju Akshatha, R. Pruthvish, Raghavendra G Amachawadi, Chandrashekar Srinivasa, Asad Syed, Abdallah M. Elgorban, Abdulaziz A. Al Kheraif, Joaquín Ortega-Castro, Juan Frau, Norma Flores-Holguín, Chandan Shivamallu, Shiva Prasad Kollur, Daniel Glossman-Mitnik
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Chemistry
Subjects:
Alzheimer’s disease
neuropathology
neurofibrillary tangles
amyloid plaques
molecular docking
computational pharmacokinetics
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.741037/full

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https://www.frontiersin.org/articles/10.3389/fchem.2021.741037/full

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