Comparing oscillometric and tonometric methods to assess pulse wave velocity: a population-based study
AbstractBackground Oscillometric pulse wave velocity (o-PWV) represents an attractive, non invasive and non operator-dependent method to estimate arterial stiffness. Tonometric carotid-femoral measurements (cf-PWV),are considered the gold-standard for non-invasive aortic stiffness assessment. To dat...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | Annals of Medicine |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2020.1794538 |
| _version_ | 1797385721373261824 |
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| author | Rosaria Del Giorno Chiara Troiani Sofia Gabutti Kevyn Stefanelli Luca Gabutti |
| author_facet | Rosaria Del Giorno Chiara Troiani Sofia Gabutti Kevyn Stefanelli Luca Gabutti |
| author_sort | Rosaria Del Giorno |
| collection | DOAJ |
| description | AbstractBackground Oscillometric pulse wave velocity (o-PWV) represents an attractive, non invasive and non operator-dependent method to estimate arterial stiffness. Tonometric carotid-femoral measurements (cf-PWV),are considered the gold-standard for non-invasive aortic stiffness assessment. To date, no studies in the general population comparing the two methods have been performed.Methods and Results 1162 subjects were analysed. O-PWV and cf-PWV showed a mean difference of −0.31 m/sec(p ≤ 0.001). No significant differences between cf-PWV and o-PWVs were observed in patients without cardiovascular risk factors. The Bland and Altman analysis showed a moderate agreement between 24 h-o-PWV and cf-PWV (mean difference −0.99, LoA 4.23 to −6.22m/s). O-PWVs underestimate and overestimate arterial stiffness under and over 50 years respectively(p ≤ 0.001). Systolic blood pressure (SBP) and age differently impact cf-PWV and in office o-PWV variability (r2 0.35 and 0.88 respectively). In younger subjects a strong relationship between o-PWV and SBP reducing as age increases was found. Analysing the impact of age, an opposite trend was noticed.Conclusions Oscillometric PWV estimates provide reliable values in the general population. An o-PWV tendency to underestimate arterial stiffness in younger subjects and in subjects with diseases known to increase arterial stiffness and to overestimate it with increasing age was found, even if scarcely relevant in clinical perspective. Overall the present findings underline an acceptable and satisfactory agreement between oscillometric and tonometric methods for the PWV assessment.KEY MESSAGESOscillometric and tonometric PWV estimates showed a good and satisfactory agreement in the general population, above all in subjects without cardiovascular risk factors or a documented vascular damage.In comparison with tonometric values, oscillometric PWV estimates showed, however, the tendency to underestimate arterial stiffness in younger subjects and to overestimate it with increasing age, while diverging when diseases known to increase arterial stiffness are present.The magnitude of differences in PWV estimates between tonometric and oscillometric methods found in the general population appears most likely not to be significant in everyday clinical practice. |
| first_indexed | 2024-03-08T21:58:20Z |
| format | Article |
| id | doaj.art-be9652586c1e40778e1ab267ba90621d |
| institution | Directory Open Access Journal |
| issn | 0785-3890 1365-2060 |
| language | English |
| last_indexed | 2024-03-08T21:58:20Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj.art-be9652586c1e40778e1ab267ba90621d2023-12-19T16:46:27ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602021-01-0153111610.1080/07853890.2020.1794538Comparing oscillometric and tonometric methods to assess pulse wave velocity: a population-based studyRosaria Del Giorno0Chiara Troiani1Sofia Gabutti2Kevyn Stefanelli3Luca Gabutti4Department of Internal Medicine, Clinical Research Unit, Regional Hospital of Bellinzona and Valli, Ente Ospedaliero Cantonale, Bellinzona, SwitzerlandDepartment of Internal Medicine, Clinical Research Unit, Regional Hospital of Bellinzona and Valli, Ente Ospedaliero Cantonale, Bellinzona, SwitzerlandDepartment of Internal Medicine, Clinical Research Unit, Regional Hospital of Bellinzona and Valli, Ente Ospedaliero Cantonale, Bellinzona, SwitzerlandDepartment of Social Sciences and Economics, Sapienza University of Rome, Rome, ItalyDepartment of Internal Medicine, Clinical Research Unit, Regional Hospital of Bellinzona and Valli, Ente Ospedaliero Cantonale, Bellinzona, SwitzerlandAbstractBackground Oscillometric pulse wave velocity (o-PWV) represents an attractive, non invasive and non operator-dependent method to estimate arterial stiffness. Tonometric carotid-femoral measurements (cf-PWV),are considered the gold-standard for non-invasive aortic stiffness assessment. To date, no studies in the general population comparing the two methods have been performed.Methods and Results 1162 subjects were analysed. O-PWV and cf-PWV showed a mean difference of −0.31 m/sec(p ≤ 0.001). No significant differences between cf-PWV and o-PWVs were observed in patients without cardiovascular risk factors. The Bland and Altman analysis showed a moderate agreement between 24 h-o-PWV and cf-PWV (mean difference −0.99, LoA 4.23 to −6.22m/s). O-PWVs underestimate and overestimate arterial stiffness under and over 50 years respectively(p ≤ 0.001). Systolic blood pressure (SBP) and age differently impact cf-PWV and in office o-PWV variability (r2 0.35 and 0.88 respectively). In younger subjects a strong relationship between o-PWV and SBP reducing as age increases was found. Analysing the impact of age, an opposite trend was noticed.Conclusions Oscillometric PWV estimates provide reliable values in the general population. An o-PWV tendency to underestimate arterial stiffness in younger subjects and in subjects with diseases known to increase arterial stiffness and to overestimate it with increasing age was found, even if scarcely relevant in clinical perspective. Overall the present findings underline an acceptable and satisfactory agreement between oscillometric and tonometric methods for the PWV assessment.KEY MESSAGESOscillometric and tonometric PWV estimates showed a good and satisfactory agreement in the general population, above all in subjects without cardiovascular risk factors or a documented vascular damage.In comparison with tonometric values, oscillometric PWV estimates showed, however, the tendency to underestimate arterial stiffness in younger subjects and to overestimate it with increasing age, while diverging when diseases known to increase arterial stiffness are present.The magnitude of differences in PWV estimates between tonometric and oscillometric methods found in the general population appears most likely not to be significant in everyday clinical practice.https://www.tandfonline.com/doi/10.1080/07853890.2020.1794538Arterial stiffnesspulse wave velocitytonometric methodoscillometric methodvascular ageingcomparative analysis |
| spellingShingle | Rosaria Del Giorno Chiara Troiani Sofia Gabutti Kevyn Stefanelli Luca Gabutti Comparing oscillometric and tonometric methods to assess pulse wave velocity: a population-based study Annals of Medicine Arterial stiffness pulse wave velocity tonometric method oscillometric method vascular ageing comparative analysis |
| title | Comparing oscillometric and tonometric methods to assess pulse wave velocity: a population-based study |
| title_full | Comparing oscillometric and tonometric methods to assess pulse wave velocity: a population-based study |
| title_fullStr | Comparing oscillometric and tonometric methods to assess pulse wave velocity: a population-based study |
| title_full_unstemmed | Comparing oscillometric and tonometric methods to assess pulse wave velocity: a population-based study |
| title_short | Comparing oscillometric and tonometric methods to assess pulse wave velocity: a population-based study |
| title_sort | comparing oscillometric and tonometric methods to assess pulse wave velocity a population based study |
| topic | Arterial stiffness pulse wave velocity tonometric method oscillometric method vascular ageing comparative analysis |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2020.1794538 |
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