Porphyromonas gingivalis aggravates colitis via a gut microbiota-linoleic acid metabolism-Th17/Treg cell balance axis

Abstract Periodontitis is closely related to inflammatory bowel disease (IBD). An excessive and non-self-limiting immune response to the dysbiotic microbiome characterizes the two. However, the underlying mechanisms that overlap still need to be clarified. We demonstrate that the critical periodonta...

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Bibliographic Details
Main Authors: Lu Jia, Yiyang Jiang, Lili Wu, Jingfei Fu, Juan Du, Zhenhua Luo, Lijia Guo, Junji Xu, Yi Liu
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45473-y

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