Evaluation and comparison of computational tools for RNA-seq isoform quantification

Evaluation and comparison of computational tools for RNA-seq isoform quantification

Abstract Background Alternatively spliced transcript isoforms are commonly observed in higher eukaryotes. The expression levels of these isoforms are key for understanding normal functions in healthy tissues and the progression of disease states. However, accurate quantification of expression at the...

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Bibliographic Details
Main Authors: Chi Zhang, Baohong Zhang, Lih-Ling Lin, Shanrong Zhao
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Genomics
Subjects:
RNA-seq
Quantification
Isoform
Data analysis
RSEM
Salmon
Online Access:http://link.springer.com/article/10.1186/s12864-017-4002-1

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