The miR-23b/27b/24-1 Cluster Inhibits Hepatic Fibrosis by Inactivating Hepatic Stellate CellsSummary

The miR-23b/27b/24-1 Cluster Inhibits Hepatic Fibrosis by Inactivating Hepatic Stellate CellsSummary

Background & Aims: Hepatic fibrosis is characterized by hepatic stellate cell (HSC) activation and transdifferentiation-mediated extracellular matrix (ECM) deposition, which both contribute to cirrhosis. However, no antifibrotic regimen is available in the clinic. microRNA-23b/27b/24-1 clust...

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Bibliographic Details
Main Authors: Lin-Yan Wan, Hu Peng, Yi-Ran Ni, Xue-Ping Jiang, Jiao-Jiao Wang, Yan-Qiong Zhang, Lan Ma, Rui Li, Lin Han, Yong Tan, Jun-Ming Li, Wen-Li Cai, Wen-Fang Yuan, Jia-Jie Liang, Lu Huang, Xu Wu, Quan Zhou, Qi-Ni Cheng, Xue Yang, Meng-Yuan Liu, Wen-Bing Ai, Chang-Bai Liu, Hongbing Zhang, Jiang-Feng Wu
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
miR-23b/27b/24-1 Cluster
TGF-β2
Gremlin1
LOX
Itgα2/5
Hepatic Stellate Cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X22000169

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http://www.sciencedirect.com/science/article/pii/S2352345X22000169

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