Dithiocarbazate ligands and their Ni(II) complexes with potential biological activity: Structural, antitumor and molecular docking study

Dithiocarbazate ligands and their Ni(II) complexes with potential biological activity: Structural, antitumor and molecular docking study

In the search for new metal complexes with antitumor potential, two dithiocarbazate ligands derived from 1,1,1-trifluoro-2,4-pentanedione (H2L1) and (H2L2) and four Ni(II) complexes, [Ni(L1)PPh3] (1), [Ni(L1)Py] (2), [Ni(L2)PPh3] (3), and [Ni(L2)Py] (4), were successfully synthesized and investigate...

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Bibliographic Details
Main Authors: Cássia de Q. O. Cavalcante, Tales H. A. da Mota, Diêgo M. de Oliveira, Érica C. M. Nascimento, João B. L. Martins, Fabio Pittella-Silva, Claudia C. Gatto
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
Ni(II) complexes
dithiocarbazate
crystal structure
mass spectrometry
Hirshfeld surface
antitumor activity
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1146820/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1146820/full

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