Coactivation of Lower Limb Muscles during Gait in Patients with Multiple Sclerosis.
BACKGROUND:Coactivation of agonist and antagonist lower limb muscles during gait stiffens joints and ensures stability. In patients with multiple sclerosis, coactivation of lower limb muscles might be a compensatory mechanism to cope with impairments of balance and gait. OBJECTIVE:The aim of this st...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2016-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4919099?pdf=render |
| _version_ | 1811324946652069888 |
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| author | Julien Boudarham Sophie Hameau Raphael Zory Alexandre Hardy Djamel Bensmail Nicolas Roche |
| author_facet | Julien Boudarham Sophie Hameau Raphael Zory Alexandre Hardy Djamel Bensmail Nicolas Roche |
| author_sort | Julien Boudarham |
| collection | DOAJ |
| description | BACKGROUND:Coactivation of agonist and antagonist lower limb muscles during gait stiffens joints and ensures stability. In patients with multiple sclerosis, coactivation of lower limb muscles might be a compensatory mechanism to cope with impairments of balance and gait. OBJECTIVE:The aim of this study was to assess coactivation of agonist and antagonist muscles at the knee and ankle joints during gait in patients with multiple sclerosis, and to evaluate the relationship between muscle coactivation and disability, gait performance, dynamic ankle strength measured during gait, and postural stability. METHODS:The magnitude and duration of coactivation of agonist-antagonist muscle pairs at the knee and ankle were determined for both lower limbs (more and less-affected) in 14 patients with multiple sclerosis and 11 healthy subjects walking at a spontaneous speed, using 3D-gait analysis. RESULTS:In the patient group, coactivation was increased in the knee muscles during single support (proximal strategy) and in the ankle muscles during double support (distal strategy). The magnitude of coactivation was highest in the patients with the slowest gait, the greatest motor impairment and the most instability. CONCLUSION:Increased muscle coactivation is likely a compensatory mechanism to limit the number of degrees of freedom during gait in patients with multiple sclerosis, particularly when postural stability is impaired. |
| first_indexed | 2024-04-13T14:24:20Z |
| format | Article |
| id | doaj.art-beb1878f9d6b4ab2a5c40651f812e04c |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T14:24:20Z |
| publishDate | 2016-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-beb1878f9d6b4ab2a5c40651f812e04c2022-12-22T02:43:22ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01116e015826710.1371/journal.pone.0158267Coactivation of Lower Limb Muscles during Gait in Patients with Multiple Sclerosis.Julien BoudarhamSophie HameauRaphael ZoryAlexandre HardyDjamel BensmailNicolas RocheBACKGROUND:Coactivation of agonist and antagonist lower limb muscles during gait stiffens joints and ensures stability. In patients with multiple sclerosis, coactivation of lower limb muscles might be a compensatory mechanism to cope with impairments of balance and gait. OBJECTIVE:The aim of this study was to assess coactivation of agonist and antagonist muscles at the knee and ankle joints during gait in patients with multiple sclerosis, and to evaluate the relationship between muscle coactivation and disability, gait performance, dynamic ankle strength measured during gait, and postural stability. METHODS:The magnitude and duration of coactivation of agonist-antagonist muscle pairs at the knee and ankle were determined for both lower limbs (more and less-affected) in 14 patients with multiple sclerosis and 11 healthy subjects walking at a spontaneous speed, using 3D-gait analysis. RESULTS:In the patient group, coactivation was increased in the knee muscles during single support (proximal strategy) and in the ankle muscles during double support (distal strategy). The magnitude of coactivation was highest in the patients with the slowest gait, the greatest motor impairment and the most instability. CONCLUSION:Increased muscle coactivation is likely a compensatory mechanism to limit the number of degrees of freedom during gait in patients with multiple sclerosis, particularly when postural stability is impaired.http://europepmc.org/articles/PMC4919099?pdf=render |
| spellingShingle | Julien Boudarham Sophie Hameau Raphael Zory Alexandre Hardy Djamel Bensmail Nicolas Roche Coactivation of Lower Limb Muscles during Gait in Patients with Multiple Sclerosis. PLoS ONE |
| title | Coactivation of Lower Limb Muscles during Gait in Patients with Multiple Sclerosis. |
| title_full | Coactivation of Lower Limb Muscles during Gait in Patients with Multiple Sclerosis. |
| title_fullStr | Coactivation of Lower Limb Muscles during Gait in Patients with Multiple Sclerosis. |
| title_full_unstemmed | Coactivation of Lower Limb Muscles during Gait in Patients with Multiple Sclerosis. |
| title_short | Coactivation of Lower Limb Muscles during Gait in Patients with Multiple Sclerosis. |
| title_sort | coactivation of lower limb muscles during gait in patients with multiple sclerosis |
| url | http://europepmc.org/articles/PMC4919099?pdf=render |
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