Review: management of Parkinson's disease

David J Pedrosa, Lars Timmermann Department of Neurology, University Hospital Cologne, Cologne, Germany Abstract: Parkinson's disease (PD) is one of the most frequent neurological diseases. Despite the modern imaging and nuclear techniques which help to diagnose it in a very early stage...

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Main Authors: Pedrosa DJ, Timmermann L
Format: Article
Language:English
Published: Dove Medical Press 2013-03-01
Series:Neuropsychiatric Disease and Treatment
Online Access:http://www.dovepress.com/review-management-of-parkinson39s-disease-a12353
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author Pedrosa DJ
Timmermann L
author_facet Pedrosa DJ
Timmermann L
author_sort Pedrosa DJ
collection DOAJ
description David J Pedrosa, Lars Timmermann Department of Neurology, University Hospital Cologne, Cologne, Germany Abstract: Parkinson's disease (PD) is one of the most frequent neurological diseases. Despite the modern imaging and nuclear techniques which help to diagnose it in a very early stage and lead to a better discrimination of similar diseases, PD has remained a clinical diagnosis. The increasing number of available treatment options makes the disease management often complicated even when the presence of PD seems undoubted. In addition, nonmotor symptoms and side effects of some therapies constitute some pitfalls already in the preclinical state or at the beginnings of the disease, especially with the progressive effect on patients. Therefore, this review aimed to summarize study results and depict recommended medical treatments for the most common motor and nonmotor symptoms in PD. Additionally, emerging new therapeutic options such as continuous pump therapies, eg, with apomorphine or parenteral levodopa, or the implantation of electrodes for deep brain stimulation were also considered. Keywords: Parkinson's disease, disease management, side effects, nonmotor symptoms, DBS, pump therapies
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spelling doaj.art-beb2e00110a74aba85616cdda12e86062022-12-21T22:54:55ZengDove Medical PressNeuropsychiatric Disease and Treatment1176-63281178-20212013-03-012013default321340Review: management of Parkinson's diseasePedrosa DJTimmermann LDavid J Pedrosa, Lars Timmermann Department of Neurology, University Hospital Cologne, Cologne, Germany Abstract: Parkinson's disease (PD) is one of the most frequent neurological diseases. Despite the modern imaging and nuclear techniques which help to diagnose it in a very early stage and lead to a better discrimination of similar diseases, PD has remained a clinical diagnosis. The increasing number of available treatment options makes the disease management often complicated even when the presence of PD seems undoubted. In addition, nonmotor symptoms and side effects of some therapies constitute some pitfalls already in the preclinical state or at the beginnings of the disease, especially with the progressive effect on patients. Therefore, this review aimed to summarize study results and depict recommended medical treatments for the most common motor and nonmotor symptoms in PD. Additionally, emerging new therapeutic options such as continuous pump therapies, eg, with apomorphine or parenteral levodopa, or the implantation of electrodes for deep brain stimulation were also considered. Keywords: Parkinson's disease, disease management, side effects, nonmotor symptoms, DBS, pump therapieshttp://www.dovepress.com/review-management-of-parkinson39s-disease-a12353
spellingShingle Pedrosa DJ
Timmermann L
Review: management of Parkinson's disease
Neuropsychiatric Disease and Treatment
title Review: management of Parkinson's disease
title_full Review: management of Parkinson's disease
title_fullStr Review: management of Parkinson's disease
title_full_unstemmed Review: management of Parkinson's disease
title_short Review: management of Parkinson's disease
title_sort review management of parkinson amp 39 s disease
url http://www.dovepress.com/review-management-of-parkinson39s-disease-a12353
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