B-type natriuretic peptide testing in the emergency setting for managing acute dyspnea

INTRODUCTION The performance of B-type natriuretic peptide to accurately diagnose dyspnea of cardiac origin has been widely proved. However, its impact in clinical practice is less clear. METHODS We searched in Epistemonikos, the largest database of systematic reviews in health, which is mainta...

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Main Authors: María Morales, Gabriel Rada
Format: Article
Language:English
Published: Medwave Estudios Limitada 2019-11-01
Series:Medwave
Subjects:
Online Access:https://www.medwave.cl/link.cgi/Medwave/PuestaDia/ResEpis/7676
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author María Morales
Gabriel Rada
author_facet María Morales
Gabriel Rada
author_sort María Morales
collection DOAJ
description INTRODUCTION The performance of B-type natriuretic peptide to accurately diagnose dyspnea of cardiac origin has been widely proved. However, its impact in clinical practice is less clear. METHODS We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. We extracted data from the systematic reviews, reanalyzed data of primary studies, conducted a meta-analysis and generated a summary of findings table using the GRADE approach. RESULTS AND CONCLUSIONS We identified two systematic reviews including five studies overall, of which all were randomized trials. We concluded the use of B-type natriuretic peptide for the management of acute dyspnea in the emergency setting probably leads to a small reduction in the need for hospitalization. Additionally, it may slightly reduce mortality and intensive care unit admission, but the certainty of the evidence is low.
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spelling doaj.art-beb468144c7648f78011cea9679e5e7e2022-12-21T19:25:09ZengMedwave Estudios LimitadaMedwave0717-63842019-11-011910e7677e767710.5867/medwave.2019.10.7677B-type natriuretic peptide testing in the emergency setting for managing acute dyspneaMaría Morales0Gabriel Rada1Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Proyecto Epistemonikos, Santiago, ChileFacultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Proyecto Epistemonikos, Santiago, ChileINTRODUCTION The performance of B-type natriuretic peptide to accurately diagnose dyspnea of cardiac origin has been widely proved. However, its impact in clinical practice is less clear. METHODS We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. We extracted data from the systematic reviews, reanalyzed data of primary studies, conducted a meta-analysis and generated a summary of findings table using the GRADE approach. RESULTS AND CONCLUSIONS We identified two systematic reviews including five studies overall, of which all were randomized trials. We concluded the use of B-type natriuretic peptide for the management of acute dyspnea in the emergency setting probably leads to a small reduction in the need for hospitalization. Additionally, it may slightly reduce mortality and intensive care unit admission, but the certainty of the evidence is low.https://www.medwave.cl/link.cgi/Medwave/PuestaDia/ResEpis/7676bnpacute dyspneaepistemonikosgrade
spellingShingle María Morales
Gabriel Rada
B-type natriuretic peptide testing in the emergency setting for managing acute dyspnea
Medwave
bnp
acute dyspnea
epistemonikos
grade
title B-type natriuretic peptide testing in the emergency setting for managing acute dyspnea
title_full B-type natriuretic peptide testing in the emergency setting for managing acute dyspnea
title_fullStr B-type natriuretic peptide testing in the emergency setting for managing acute dyspnea
title_full_unstemmed B-type natriuretic peptide testing in the emergency setting for managing acute dyspnea
title_short B-type natriuretic peptide testing in the emergency setting for managing acute dyspnea
title_sort b type natriuretic peptide testing in the emergency setting for managing acute dyspnea
topic bnp
acute dyspnea
epistemonikos
grade
url https://www.medwave.cl/link.cgi/Medwave/PuestaDia/ResEpis/7676
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