Melatonin Attenuates Cisplatin-Induced Acute Kidney Injury through Dual Suppression of Apoptosis and Necroptosis

Melatonin Attenuates Cisplatin-Induced Acute Kidney Injury through Dual Suppression of Apoptosis and Necroptosis

Melatonin is well known to modulate the sleep−wake cycle. Accumulating evidence suggests that melatonin also has favorable effects such as anti-oxidant and anti-inflammatory properties in numerous disease models. It has been reported that melatonin has therapeutic effects against cisplatin...

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Bibliographic Details
Main Authors: Jong Woo Kim, Jungmin Jo, Jung-Yeon Kim, Misun Choe, Jaechan Leem, Jae-Hyung Park
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Biology
Subjects:
melatonin
cisplatin
acute kidney injury
apoptosis
necroptosis
Online Access:https://www.mdpi.com/2079-7737/8/3/64

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